Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 9PY3
TargetMu-type opioid receptor(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017698BDBM50017698(cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017698BDBM50017698(cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...)
Affinity DataKi:  0.268nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in HEK293 cell membrane incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017698BDBM50017698(cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...)
Affinity DataKi:  0.530nMAssay Description:Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017698BDBM50017698(cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...)
Affinity DataIC50: 1.5nMAssay Description:Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Guinea pig)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017698BDBM50017698(cid_71420 | Imodium | 4-[4-(4-Chloro-phenyl)-4-hyd...)
Affinity DataEC50:  58nMAssay Description:Inhibition of mu opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)