Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) for PDB: 9TFI
TargetMast/stem cell growth factor receptor Kit(Human)
University of The Pacific

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 397897BDBM397897(US9994552, Compound 108)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to KIT D816V mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMast/stem cell growth factor receptor Kit(Human)
University of The Pacific

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 397897BDBM397897(US9994552, Compound 108)
Affinity DataIC50: 1nMAssay Description:Kit wild type assay: In each well of a 384-well plate, 0.2 ng/ul final (2 nM) of wild type Kit (Carna Bioscience 08-156) was incubated in a total of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMast/stem cell growth factor receptor Kit [D816V](Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 397897BDBM397897(US9994552, Compound 108)
Affinity DataIC50: 1nMAssay Description:Kit D816V assay: In each well of a 384-well plate, 0.04 ng/ul (0.5 nM) of D816V Kit (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMast/stem cell growth factor receptor Kit(Human)
University of The Pacific

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 397897BDBM397897(US9994552, Compound 108)
Affinity DataKd:  4.40nMAssay Description:Binding affinity to KIT V816H mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMast/stem cell growth factor receptor Kit(Human)
University of The Pacific

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 397897BDBM397897(US9994552, Compound 108)
Affinity DataKd:  11nMAssay Description:Binding affinity to KIT V559D mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMast/stem cell growth factor receptor Kit(Human)
University of The Pacific

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 397897BDBM397897(US9994552, Compound 108)
Affinity DataKd:  20nMAssay Description:Binding affinity to KIT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMast/stem cell growth factor receptor Kit(Human)
University of The Pacific

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 397897BDBM397897(US9994552, Compound 108)
Affinity DataKd:  130nMAssay Description:Binding affinity to KIT V559D/T670I mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)