Compile Data Set for Download or QSAR
Report error Found 226 of affinity data for UniProtKB/TrEMBL: P00956
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50524451(CHEMBL4553017)
Affinity DataKi:  1.20nMAssay Description:Inhibition of recombinant Escherichia coli BL21(DE3) isoleucyl-tRNA synthetase expressed in Escherichia coli Rosetta 2 (DE3) assessed as reduction in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50222902(CHEMBL1163069)
Affinity DataKi:  1.90nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Isoleucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escheri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50290686(9-(4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-3-((...)
Affinity DataKi:  2.5nMAssay Description:Competitive inhibition of Escherichia coli Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50524451(CHEMBL4553017)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant Escherichia coli BL21(DE3) isoleucyl-tRNA synthetase expressed in Escherichia coli Rosetta 2 (DE3) assessed as reduction in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50524360(CHEMBL3265242)
Affinity DataKi:  17nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726177(US12247004, Compound ANASIA-041-1)
Affinity DataIC50: 17.7nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726265(US12247004, Compound ANASIA-103-1)
Affinity DataIC50: 19.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726297(US12247004, Compound ANASIA-124-1)
Affinity DataIC50: 21.3nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726132(US12247004, Compound ANASIA-011-1)
Affinity DataIC50: 26.2nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726113(US12247004, Compound ANASIA-002-1)
Affinity DataIC50: 27.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726261(US12247004, Compound ANASIA-100-1)
Affinity DataIC50: 27.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726251(US12247004, Compound ANASIA-095-1)
Affinity DataIC50: 29nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726126(US12247004, Compound ANASIA-008-1)
Affinity DataIC50: 30.6nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726260(US12247004, Compound ANASIA-100)
Affinity DataIC50: 32.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726230(US12247004, Compound ANASIA-081-1)
Affinity DataIC50: 33.9nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726292(US12247004, Compound ANASIA-121-1)
Affinity DataIC50: 41.7nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726206(US12247004, Compound ANASIA-062-1)
Affinity DataIC50: 47.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726247(US12247004, Compound ANASIA-092-1)
Affinity DataIC50: 48.4nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50524354(CHEMBL3265243)
Affinity DataKi:  55nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726140(US12247004, Compound ANASIA-015-1)
Affinity DataIC50: 56.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726116(US12247004, Compound ANASIA-003-1)
Affinity DataIC50: 61.5nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726281(US12247004, Compound ANASIA-114-1)
Affinity DataIC50: 61.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726123(US12247004, Compound ANASIA-007-1)
Affinity DataIC50: 63.3nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726183(US12247004, Compound ANASIA-044-1)
Affinity DataIC50: 71nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726317(US12247004, Compound ANASIA-136-1)
Affinity DataIC50: 71.8nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726131(US12247004, Compound ANASIA-011)
Affinity DataIC50: 71.9nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726257(US12247004, Compound ANASIA-099)
Affinity DataIC50: 72.2nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726240(US12247004, Compound ANASIA-088-1)
Affinity DataIC50: 75.3nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726188(US12247004, Compound ANASIA-047-1)
Affinity DataIC50: 76.4nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726138(US12247004, Compound ANASIA-014-1)
Affinity DataIC50: 81.1nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726135(US12247004, Compound ANASIA-012-1)
Affinity DataIC50: 87.4nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50544145(CHEMBL4636583)
Affinity DataKi:  88nMAssay Description:Inhibition of Escherichia coli BL21(DE3) ileRS overexpressed in Escherichia coli Rosetta2(DE3) assessed as reduction in tRNA aminoacylation preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726118(US12247004, Compound ANASIA-004)
Affinity DataIC50: 91.6nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726115(US12247004, Compound ANASIA-003)
Affinity DataIC50: 92.9nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726312(US12247004, Compound ANASIA-133-1)
Affinity DataIC50: 97.3nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726219(US12247004, Compound ANASIA-074)
Affinity DataIC50: 99.2nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726288(US12247004, Compound ANASIA-119-1)
Affinity DataIC50: 99.7nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726271(US12247004, Compound ANASIA-107-1)
Affinity DataIC50: 106nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726112(US12247004, Compound ANASIA-002)
Affinity DataIC50: 110nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726181(US12247004, Compound ANASIA-043-1)
Affinity DataIC50: 112nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50544146(CHEMBL4648043)
Affinity DataKi:  114nMAssay Description:Inhibition of Escherichia coli BL21(DE3) ileRS overexpressed in Escherichia coli Rosetta2(DE3) assessed as reduction in tRNA aminoacylation preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726258(US12247004, Compound ANASIA-099-1)
Affinity DataIC50: 124nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726273(US12247004, Compound ANASIA-108-1)
Affinity DataIC50: 127nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726154(US12247004, Compound ANASIA-024-1)
Affinity DataIC50: 141nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726213(US12247004, Compound ANASIA-068)
Affinity DataIC50: 141nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726215(US12247004, Compound ANASIA-070)
Affinity DataIC50: 143nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726125(US12247004, Compound ANASIA-008)
Affinity DataIC50: 144nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726145(US12247004, Compound ANASIA-017)
Affinity DataIC50: 145nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726255(US12247004, Compound ANASIA-098-1)
Affinity DataIC50: 148nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

TargetIsoleucine--tRNA ligase(Escherichia coli (strain K12))
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM726129(US12247004, Compound ANASIA-009-2)
Affinity DataIC50: 149nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
US Patent

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