Compile Data Set for Download or QSAR
Report error Found 12 of affinity data for UniProtKB/TrEMBL: P06709
TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
University of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM50039492(CHEMBL1231498)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to Escherichia coli biotin protein ligaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
University of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM50039492(CHEMBL1231498)
Affinity DataKi:  87nMAssay Description:Inhibition of Escherichia coli recombinant BPL using 3H-biotin as substrate after 10 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
University of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM161472(US9108978, 2.02)
Affinity DataKi:  225nM ΔG°:  -39.5kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
Go to US Patent

TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
University of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM161472(US9108978, 2.02)
Affinity DataKi:  420nM ΔG°:  -37.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
Go to US Patent

TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
University of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM161467(US9108978, 3.25)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
Go to US Patent

TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
University of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM161468(US9108978, 6.09)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
Go to US Patent

TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
University of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM161469(US9108978, 6.07)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
Go to US Patent

TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
University of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM161470(US9108978, 4.01)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
Go to US Patent

TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
University of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM161467(US9108978, 3.25)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
Go to US Patent

TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
University of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM161468(US9108978, 6.09)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
Go to US Patent

TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
University of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM161469(US9108978, 6.07)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
Go to US Patent

TargetBifunctional ligase/repressor BirA(Escherichia coli (strain K12))
University of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM161470(US9108978, 4.01)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2016
Entry Details
Go to US Patent