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TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694660BDBM694660(US20240294535, Compound 15)
Affinity DataIC50: 0.00100nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694666BDBM694666(US20240294535, Compound 21)
Affinity DataIC50: 0.00100nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694663BDBM694663(US20240294535, Compound 18)
Affinity DataIC50: 0.00100nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694657BDBM694657(US20240294535, Compound 12)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694658BDBM694658(US20240294535, Compound 13)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694655BDBM694655(US20240294535, Compound 10)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694653BDBM694653(US20240294535, Compound 8)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694654BDBM694654(US20240294535, Compound 9)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694667BDBM694667(US20240294535, Compound 22)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694668BDBM694668(US20240294535, Compound 23)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694665BDBM694665(US20240294535, Compound 20)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694664BDBM694664(US20240294535, Compound 19)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694661BDBM694661(US20240294535, Compound 16)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694662BDBM694662(US20240294535, Compound 17)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694673BDBM694673(US20240294535, Compound 28)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694671BDBM694671(US20240294535, Compound 26)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694672BDBM694672(US20240294535, Compound 27)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694669BDBM694669(US20240294535, Compound 24)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694670BDBM694670(US20240294535, Compound 25)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694651BDBM694651(US20240294535, Compound 6)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694652BDBM694652(US20240294535, Compound 7)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694650BDBM694650(US20240294535, Compound 5)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694647BDBM694647(US20240294535, Compound 2)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694648BDBM694648(US20240294535, Compound 3)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694646BDBM694646(US20240294535, Compound 1)
Affinity DataIC50: 0.00200nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694659BDBM694659(US20240294535, Compound 14)
Affinity DataIC50: 0.00300nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694656BDBM694656(US20240294535, Compound 11)
Affinity DataIC50: 0.00300nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 694649BDBM694649(US20240294535, Compound 4)
Affinity DataIC50: 0.00300nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50146167BDBM50146167(Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...)
Affinity DataIC50: 0.00400nMAssay Description:Experimental methods: Enzyme reaction substrate, poly(Glu, Tyr)sodium salt (Glu:Tyr=4:1) was diluted with potassium-free phosphate buffered saline (P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50589142BDBM50589142(CHEMBL5184459)
Affinity DataIC50: 0.0190nMAssay Description:Inhibition of human recombinant c-MET in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50589141BDBM50589141(CHEMBL5174958)
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of human recombinant c-MET in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 164488BDBM164488(US9066954, 373)
Affinity DataKi:  0.100nM ΔG°:  -57.5kJ/molepH: 8.0 T: 2°CAssay Description:A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50165469BDBM50165469(CHEMBL3797911)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50165469BDBM50165469(CHEMBL3797911)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 60 mins by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50091353BDBM50091353(CHEMBL3582305)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of C-Met (unknown origin) using polu (Glu,Tyr)4:1 substrate after 30 mins incubation by multi-well spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50146167BDBM50146167(Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50146167BDBM50146167(Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human Nav1.2 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50146167BDBM50146167(Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50146167BDBM50146167(Capmatinib | INC-280 | INCB-28060 | NVP-INC280 | U...)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 669888BDBM669888(US20240132517, Example TPX-0022 | Example 5 of WO...)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50660171BDBM50660171(CHEMBL6133512)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of c-MET (unknown origin) incubated for 60 mins by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 60589BDBM60589(6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4...)
Affinity DataKd:  0.190nMAssay Description:Binding constant for MET kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50165469BDBM50165469(CHEMBL3797911)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 99273BDBM99273(US8497368, 65)
Affinity DataIC50: 0.200nMAssay Description:The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2013
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50384024BDBM50384024(CHEMBL2032280 | CHEMBL2079349)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 344393BDBM344393((E)-N1-(3-fluoro-4-(6-methoxy-7-(3-(piperidin-1-yl...)
Affinity DataIC50: 0.200nMAssay Description:c-Met Kinase Activity was Measured with an ELISA Reader. The Specific Operation as Follows:To the plate filled with 0.25 mg/mL PGT, the compounds, 50...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2019
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50306682BDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2018
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 99280BDBM99280(US8497368, 72)
Affinity DataIC50: 0.200nMAssay Description:The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2013
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50668920BDBM50668920(CHEMBL6188807)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human c-MET D1228N mutant (956 to end residues) extracted from baculovirus infected Sf9 cells using 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Yunbaiyao Zhengwu Science and Technology (Shanghai) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50347672BDBM50347672(CHEMBL1802904)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human recombinant c-Met-catalyzed phosphorylation of N-biotinylated peptide (EQEDEPEGDYFEWLE-CONH2) by time-resolved fluorescence reson...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
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