Compile Data Set for Download or QSAR
Report error Found 106 for UniProtKB: P14100
LigandPNGBDBM50073692(5-methyl-2-(4-methylpentyl)-(6aR,9aS)-3,4,5,8-tetr...)
Affinity DataIC50: 6nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073694((R)-7-Isopropyl-5-methyl-2-(4-methyl-pentyl)-7,8-d...)
Affinity DataIC50: 12nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50059032((6aR,9aS)-2-(3-methylbutyl)-5,6a,7,8,9,9a-hexahydr...)
Affinity DataIC50: 14nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073701(2'-hexyl-5'-methylspiro[cyclopentane-1,7'-(4',5',7...)
Affinity DataIC50: 14nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073695((R)-7-Isopropyl-5-methyl-2-(3-methyl-butyl)-7,8-di...)
Affinity DataIC50: 15nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073700((R)-2-Hexyl-7-isopropyl-5-methyl-7,8-dihydro-3H,5H...)
Affinity DataIC50: 25nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073703(2-Hexyl-5,7,7-trimethyl-7,8-dihydro-3H,5H-imidazo[...)
Affinity DataIC50: 25nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073696(5-methyl-2-pentyl-(6aR,9aS)-3,4,5,8-tetrahydrocycl...)
Affinity DataIC50: 31nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073702(2-heptyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocycl...)
Affinity DataIC50: 33nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50059062(2-hexyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50: 36nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073697(5-methyl-2-(1-propylbutyl)-(6aR,9aS)-3,4,5,8-tetra...)
Affinity DataIC50: 60nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073704(2-butyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50: 110nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50289464(3'-benzyl-2'-(4-cyclohexylphenyl)-5'-methylspiro[c...)
Affinity DataIC50: 110nMAssay Description:Inhibition of bovine aorta phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50073693(2-(1-ethylpropyl)-5-methyl-(6aR,9aS)-3,4,5,8-tetra...)
Affinity DataIC50: 150nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50241303(ethyl hydrogen (1-(3-(1-methyl-7-oxo-3-propyl-6,7-...)
Affinity DataIC50: 156nMAssay Description:Inhibition of phosphodiesterase 1 from bovine heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073698(5-methyl-2-octyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50: 160nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50111900(CHEMBL1339 | Levitra | 4-[4-Ethoxy-3-(5-methyl-4-o...)
Affinity DataIC50: 180nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146545(2-[6-(3,4-Dimethoxy-benzylamino)-7-ethyl-7H-purin-...)
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against phosphodiesterase 1 from bovine, calmodulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073699(2-ethyl-5-methyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclo...)
Affinity DataIC50: 295nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50111897(2-(2-Ethoxy-phenyl)-5-methyl-7-propyl-3H-imidazo[5...)
Affinity DataIC50: 300nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50111902(2-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 300nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50059047(5-methyl-2-propyl-(6aR,9aS)-3,4,5,8-tetrahydrocycl...)
Affinity DataIC50: 350nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 400nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 561nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 739nMAssay Description:Inhibition of phosphodiesterase 1 from bovine heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of bovine aorta PDE1 (Phosphodiesterase 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50059028(2,5-dimethyl-(6aR,9aS)-3,4,5,8-tetrahydrocyclopent...)
Affinity DataIC50: 1.25E+3nMAssay Description:Optimum inhibitory concentration required to inhibit c-GMP specific phosphodiesterase 1 (PDE1) of bovine aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50421642(CHEMBL516604)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory concentration against phosphodiesterase 1 from bovine, calmodulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50117701(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1 (PDE1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50117712(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1 (PDE1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50475621(CHEMBL371434)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandPNGBDBM14769(6-[4-(difluoromethoxy)-3-methoxyphenyl]-2,3-dihydr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against phosphodiesterase 1 from bovine, calmodulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against phosphodiesterase 1 from bovine, calmodulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against phosphodiesterase 1 from bovine, calmodulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM15297(N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against phosphodiesterase 1 from bovine, calmodulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine aorta PDE1 (Phosphodiesterase 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50117710(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1 (PDE1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50117704(3-Cyclopropylmethyl-8-[2-ethoxy-5-(4-methyl-pipera...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1 (PDE1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50117703(3-But-3-enyl-8-[2-ethoxy-5-(4-methyl-piperazine-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1 (PDE1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50117707(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1 (PDE1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50475612(CHEMBL201169)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandPNGBDBM50475614(CHEMBL201249)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandPNGBDBM50475620(CHEMBL372819)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandPNGBDBM50475624(CHEMBL202832)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandPNGBDBM50475615(CHEMBL425927)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandPNGBDBM50009071(Ro-23-3544 | 6-Acetyl-7-[5-(4-acetyl-3-hydroxy-2-p...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of bovine heart Phosphodiesterase 1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50141581(4-(3-Chloro-4-methoxy-benzylamino)-7-trifluorometh...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of phosphodiesterase 1 of bovine heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50475617(CHEMBL433988)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandPNGBDBM50475616(CHEMBL199878)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of bovine calmodulin-activated cAMP dependent phosphodiesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
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