Compile Data Set for Download or QSAR
Report error Found 3 of affinity data for UniProtKB/TrEMBL: P31596
TargetExcitatory amino acid transporter 2(Rattus norvegicus)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644337(CHEMBL5567160)
Affinity DataEC50:  0.5nMAssay Description:Positive allosteric modulation of EAAT2 in Sprague-Dawley rat microglial cells assessed as increase in glutamate uptake preincubated for 10 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Rattus norvegicus)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644340(CHEMBL5569996)
Affinity DataEC50:  13nMAssay Description:Positive allosteric modulation of EAAT2 in Sprague-Dawley rat microglial cells assessed as increase in glutamate uptake preincubated for 10 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Rattus norvegicus)
Drexel University College of Medicine

Curated by ChEMBL
LigandPNGBDBM50644343(CHEMBL5570919)
Affinity DataIC50: 752nMAssay Description:Negative allosteric modulation of EAAT2 in Sprague-Dawley rat microglial cells assessed as decrease in glutamate uptake preincubated for 10 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed