Compile Data Set for Download or QSAR
Report error Found 5 of affinity data for UniProtKB/TrEMBL: P47941
TargetCrk-like protein(Mus musculus)
Tufts Medical Center

Curated by ChEMBL
LigandPNGBDBM185674(Rebastinib | 4-[4-[(5-tert-butyl-2-quinolin-6-ylpy...)
Affinity DataIC50: 495nMAssay Description:Inhibition of CrkL in mouse BaF3 cells harbouring BCR-ABL1 native measured after 6 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCrk-like protein(Mus musculus)
Tufts Medical Center

Curated by ChEMBL
LigandPNGBDBM185674(Rebastinib | 4-[4-[(5-tert-butyl-2-quinolin-6-ylpy...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CrkL in mouse BaF3 cells harbouring BCR-ABL1 T315I mutant measured after 6 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCrk-like protein(Mus musculus)
Tufts Medical Center

Curated by ChEMBL
LigandPNGBDBM50237710(AMN 107 | AMN107 | 4-methyl-N-[3-(4-methyl-1H-imid...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CrkL in mouse BaF3 cells harbouring BCR-ABL1 T315I mutant measured after 6 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCrk-like protein(Mus musculus)
Tufts Medical Center

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CrkL in mouse BaF3 cells harbouring BCR-ABL1 T315I mutant measured after 6 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCrk-like protein(Mus musculus)
Tufts Medical Center

Curated by ChEMBL
LigandPNGBDBM86734(CAS_220127-57-1 | NSC_0 | Gleevec)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CrkL in mouse BaF3 cells harbouring BCR-ABL1 T315I mutant measured after 6 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed