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TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546288(CHEMBL4743437)
Affinity DataIC50: 10nMAssay Description:Inhibition of CD39 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50546280(CHEMBL4761506)
Affinity DataIC50: 10nMAssay Description:Inhibition of CD39 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527134(CHEMBL4471306 | US20230295213, Compound a)
Affinity DataIC50: 10nMAssay Description:Inhibition of CD39 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50615669(CHEMBL5277365)
Affinity DataIC50: 50nMAssay Description:Inhibition of human NTPDase1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50615668(CHEMBL5283491)
Affinity DataIC50: 500nMAssay Description:Inhibition of human NTPDase1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50552128(CHEMBL4787368)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human CD39 expressed in green monkey Cos-7 cells using ATP as substrate preincubated for 3 mins followed by substrate addition by malac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50010311(CHEMBL2364580)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human CD39 using ATP as substrate preincubated for 3 mins followed by substrate addition and measured after 10 to 15 mins by Malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM511076(2-(((2R,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human CD39 expressed in human K562 cells incubated for 40 mins in presence of ATP by Kinase Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50561221(CHEMBL4745473 | US11377469, Example 95)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CD39 expressed in CHO cells incubated for 4 hrs before addition of AMP and further incubated for 60 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human CD39 expressed in green monkey Cos-7 cells using ATP as substrate preincubated for 3 mins followed by substrate addition by malac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50527649(CHEMBL4467828)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CD39 expressed in CHO cells using ATP as substrate preincubated for 1 hr followed by substrate addition and measured after 50 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50187685(CHEMBL597418)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human NTPDase1 expressed in CHO cells using ADP as substrate incubated for 10 mins by capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2017
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50552126(CHEMBL4797422)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human CD39 using ATP as substrate preincubated for 3 mins followed by substrate addition and measured after 10 to 15 mins by Malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50552127(CHEMBL4750781)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human CD39 using ATP as substrate preincubated for 3 mins followed by substrate addition and measured after 10 to 15 mins by Malachite ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276786(CHEMBL4172790)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276788(CHEMBL4162261)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276790(CHEMBL4174849)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276791(CHEMBL4164891)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276781(CHEMBL4159729)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276783(CHEMBL4169839)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276785(CHEMBL4164185)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276782(CHEMBL4165654)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276784(CHEMBL4159530)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276789(CHEMBL4175913)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276787(CHEMBL4173693)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276780(CHEMBL4172933)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50276794(CHEMBL4161473)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50552127(CHEMBL4750781)
Affinity DataKi:  800nMAssay Description:Inhibition of human CD39 using ATP as substrate preincubated for 3 mins followed by substrate addition and measured after 10 to 15 mins by Dixon and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50010311(CHEMBL2364580)
Affinity DataKi:  800nMAssay Description:Inhibition of human CD39 using ATP as substrate preincubated for 3 mins followed by substrate addition and measured after 10 to 15 mins by Cheng-Prus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50552126(CHEMBL4797422)
Affinity DataKi:  900nMAssay Description:Inhibition of human CD39 using ATP as substrate preincubated for 3 mins followed by substrate addition and measured after 10 to 15 mins by Dixon and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50307836(Sodium 1-Amino-4-(2-anthracenylamino)-9,10-dioxo-9...)
Affinity DataKi:  2.59E+3nMAssay Description:Inhibition of human NTPdase1 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50268725(sodium 1-amino-4-(4-hydroxyphenylamino)-9,10-dioxo...)
Affinity DataKi:  1.07E+4nMAssay Description:Inhibition of human NTPdase1 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50179358(CHEMBL1206141)
Affinity DataKi:  1.10E+4nMAssay Description:Competitive inhibition of human CD39 using ATP as substrate preincubated for 3 mins followed by substrate addition and measured after 15 mins by Dixo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50307835(Sodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9...)
Affinity DataKi: >4.00E+4nMAssay Description:Inhibition of human NTPdase1 by capillary electrophoresis methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262250(4-[3-((2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimi...)
Affinity DataKi:  5.52E+4nMAssay Description:Inhibition of human NTPDase 1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262372(4-[3-((2S,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-...)
Affinity DataKi:  1.54E+5nMAssay Description:Inhibition of human NTPDase 1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262373(4-[4-((2S,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-...)
Affinity DataKi:  1.61E+5nMAssay Description:Inhibition of human NTPDase 1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262251(4-[4-((2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimi...)
Affinity DataKi:  1.82E+5nMAssay Description:Inhibition of human NTPDase 1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Arcus Biosciences

Curated by ChEMBL
LigandPNGBDBM50262252(2-[(2S,3R,4S,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin...)
Affinity DataKi:  7.86E+5nMAssay Description:Inhibition of human NTPDase 1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed