Compile Data Set for Download or QSAR
Report error Found 105 of affinity data for UniProtKB/TrEMBL: Q92905
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  5.51E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50514114(CHEMBL4528101)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of CSN5 (unknown origin) using fluorescence-labeled CRL substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50514115(CHEMBL4447716)
Affinity DataIC50: 60nMAssay Description:Inhibition of CSN5 (unknown origin) using fluorescence-labeled CRL substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50060898(5,8-dihydroxy-1,4-naphthoquinone | 5,8-Dihydroxy-[...)
Affinity DataIC50: 170nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 190nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM400994(US10005735, Compound 7)
Affinity DataIC50: 200nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50597697(CHEBI:2578 | E103 | ALKANNIN)
Affinity DataIC50: 270nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264453(CHEMBL4088568)
Affinity DataIC50: 300nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM401023(US10005735, Compound 21)
Affinity DataIC50: 350nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 410nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50033741(1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2...)
Affinity DataIC50: 430nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264426(CHEMBL4095913)
Affinity DataIC50: 500nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264415(CHEMBL4096289)
Affinity DataIC50: 500nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM401020(US10005735, Compound 19)
Affinity DataIC50: 500nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50033722(CHEMBL9416 | Isobutyric acid (R)-1-(5,8-dihydroxy-...)
Affinity DataIC50: 600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50597697(CHEBI:2578 | E103 | ALKANNIN)
Affinity DataIC50: 800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50060898(5,8-dihydroxy-1,4-naphthoquinone | 5,8-Dihydroxy-[...)
Affinity DataIC50: 910nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50033741(1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2...)
Affinity DataIC50: 1.07E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50033722(CHEMBL9416 | Isobutyric acid (R)-1-(5,8-dihydroxy-...)
Affinity DataIC50: 1.17E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264491(CHEMBL4101230)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50363755(DEOXYSHIKONIN)
Affinity DataIC50: 2.51E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264484(CHEMBL4084782)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264420(CHEMBL4100384)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM400998(US10005735, Compound 11)
Affinity DataIC50: 4.00E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM401029(US10005735, Compound 27)
Affinity DataIC50: 4.40E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50363755(DEOXYSHIKONIN)
Affinity DataIC50: 4.81E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM401027(US10005735, Compound 25)
Affinity DataIC50: 4.90E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264421(CHEMBL4099434)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM400997(US10005735, Compound 10)
Affinity DataIC50: 6.90E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264417(CHEMBL4104719)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264455(CHEMBL4060337)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM401006(US10005735, Compound 15)
Affinity DataIC50: 7.00E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM401021(US10005735, Compound 20)
Affinity DataIC50: 7.00E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264503(CHEMBL4100994)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM401026(US10005735, Compound 24)
Affinity DataIC50: 7.30E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM401033(US10005735, Compound 31)
Affinity DataIC50: 7.40E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM401028(US10005735, Compound 26)
Affinity DataIC50: 8.00E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM224013(8-Mercaptoquinoline (8TQ) | US10005735, Example 8T...)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264425(CHEMBL4095417)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM401007(US10005735, Compound 16)
Affinity DataIC50: 1.10E+4nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50645454(CHEMBL5572586)
Affinity DataIC50: 1.26E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50645453(CHEMBL5574229)
Affinity DataIC50: 1.35E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM401034(US10005735, Compound 32)
Affinity DataIC50: 1.38E+4nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50645453(CHEMBL5574229)
Affinity DataIC50: 1.49E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264481(CHEMBL4065318)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM400988(US10005735, Compound 1)
Affinity DataIC50: 1.50E+4nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM400991(US10005735, Compound 4)
Affinity DataIC50: 1.50E+4nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264424(CHEMBL4078891)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50264483(CHEMBL4105598)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM400995(US10005735, Compound 8)
Affinity DataIC50: 1.60E+4nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
Go to US Patent

Displayed 1 to 50 (of 105 total ) | Next | Last >>
Jump to: