Compile Data Set for Download or QSAR
Report error Found 505 of affinity data for UniProtKB/TrEMBL: Q9S446
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50195964(CHEMBL3952582)
Affinity DataKd:  8.80E+3nMAssay Description:Binding affinity to Staphylococcus aureus His6-biotinylated SrtA expressed in Escherichia coli XL1-blue using fluorescein-tagged compound after 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50196048(CHEMBL3954877)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to Staphylococcus aureus His6-biotinylated SrtA expressed in Escherichia coli XL1-blue using fluorescein-tagged compound after 15 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of recombinant Staphylococcus aureus SrtA using DabcylQALPETGEE-Edans as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant Staphylococcus aureus SrtA using DabcylQALPETGEE-Edans as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50410879(CHEMBL5268777)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant Staphylococcus aureus SrtA using DabcylQALPETGEE-Edans as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50410891(CHEMBL5290944)
Affinity DataIC50: 20nMAssay Description:Inhibition of Staphylococcus aureus SrtA catalytic domain (60 to 206 residues) using Abz-LPETGDap(Dnp)-NH2 as substrate preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50027777(CHEBI:69919 | Hydrastine)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant Staphylococcus aureus SrtA using DabcylQALPETGEE-Edans as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50410885(CHEMBL5269466)
Affinity DataIC50: 160nMAssay Description:Inhibition of Staphylococcus aureus SrtA catalytic domain (60 to 206 residues) using Abz-LPETGDap(Dnp)-NH2 as substrate preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM33314(pyridazinone, 2-10 | pyridazinone, 2-1)
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50410888(CHEMBL5268517)
Affinity DataIC50: 220nMAssay Description:Inhibition of Staphylococcus aureus SrtA catalytic domain (60 to 206 residues) using Abz-LPETGDap(Dnp)-NH2 as substrate preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM33374(pyrazolethione, 3-12)
Affinity DataIC50: 300nMAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 300nMAssay Description:Inhibition of Staphylococcus aureus SrtA deltaN24 mutant transpeptidation activity using abz-LPATG-dnp as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50: 300nMAssay Description:Irreversible inhibition of recombinant Staphylococcus aureus sortase A deltaN24 expressed in Escherichia coli BL21(DE3) cells using Abz-LPATG-Dnp as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50271717(CHEMBL4127840)
Affinity DataIC50: 360nMAssay Description:Inhibition of Staphylococcus aureus SrtA deltaN24 mutant transpeptidation activity using abz-LPATG-dnp as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant Staphylococcus aureus sortase A deltaN24 transpeptidation expressed in Escherichia coli BL21 (DE3) cells using Abz-LPATG-Dn...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50: 400nMAssay Description:Irreversible inhibition of recombinant Staphylococcus aureus sortase A deltaN24 expressed in Escherichia coli BL21(DE3) cells using Abz-LPATG-Dnp as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50410890(CHEMBL5290647)
Affinity DataIC50: 410nMAssay Description:Inhibition of Staphylococcus aureus SrtA catalytic domain (60 to 206 residues) using Abz-LPETGDap(Dnp)-NH2 as substrate preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50: 500nMAssay Description:Irreversible inhibition of recombinant Staphylococcus aureus sortase A deltaN24 expressed in Escherichia coli BL21(DE3) cells using Abz-LPATG-Dnp as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50410887(CHEMBL5290303)
Affinity DataIC50: 540nMAssay Description:Inhibition of Staphylococcus aureus SrtA catalytic domain (60 to 206 residues) using Abz-LPETGDap(Dnp)-NH2 as substrate preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542885(CHEMBL4641661)
Affinity DataIC50: 600nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542873(CHEMBL4646366)
Affinity DataIC50: 600nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50166940(NP-031112 | NP-12 | Tideglusib | med.21724, Compou...)
Affinity DataIC50: 600nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50410886(CHEMBL5279799)
Affinity DataIC50: 620nMAssay Description:Inhibition of Staphylococcus aureus SrtA catalytic domain (60 to 206 residues) using Abz-LPETGDap(Dnp)-NH2 as substrate preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542875(CHEMBL4634419)
Affinity DataIC50: 700nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542879(CHEMBL4635655)
Affinity DataIC50: 700nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM33379(pyrazolethione, 3-17)
Affinity DataIC50: 760nMAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542892(CHEMBL4638466)
Affinity DataIC50: 800nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542876(CHEMBL4647174 | US20230414581, Compound 3)
Affinity DataIC50: 800nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50410889(CHEMBL5275369)
Affinity DataIC50: 840nMAssay Description:Inhibition of Staphylococcus aureus SrtA catalytic domain (60 to 206 residues) using Abz-LPETGDap(Dnp)-NH2 as substrate preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542886(CHEMBL4634267)
Affinity DataIC50: 900nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542874(CHEMBL4645185)
Affinity DataIC50: 900nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542878(CHEMBL4647001)
Affinity DataIC50: 900nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM33348(pyridazinone, 2-35)
Affinity DataIC50: 1.00E+3nMAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542884(CHEMBL4645619)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542888(CHEMBL4634109)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542890(CHEMBL4633170)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50: 1.10E+3nMAssay Description:Irreversible inhibition of recombinant Staphylococcus aureus sortase A deltaN24 expressed in Escherichia coli BL21(DE3) cells using Abz-LPATG-Dnp as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542887(CHEMBL4637697)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542877(CHEMBL4646173)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542883(CHEMBL4643977)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM33322(pyridazinone, 2-9)
Affinity DataIC50: 1.40E+3nMAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM33330(pyridazinone, 2-17)
Affinity DataIC50: 1.50E+3nMAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542891(CHEMBL4637940)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542882(CHEMBL4639217)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542870(CHEMBL4637978)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542881(CHEMBL4633804)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50590366(CHEMBL5174805)
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of recombinant Staphylococcus aureus sortase A deltaN24 transpeptidation expressed in Escherichia coli BL21 (DE3) cells using IsdA64 to 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50542865(CHEMBL4635187)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of Staphylococcus aureus SrtA delta N24 mutant expressed in Escherichia coli BL21 (DE3) using Abz-LPATG-Dnp substrate incubated for 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM33322(pyridazinone, 2-9)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant Staphylococcus aureus wild type truncated C-terminal His6 tagged Srt A using Abz-Leu-Pro-Glu-Thr-Gly-Lys(Dnp)-NH2 as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSortase family protein(Staphylococcus aureus)
Ecole Polytechnique F�D�Rale De Lausanne

Curated by ChEMBL
LigandPNGBDBM33333(pyridazinone, 2-20)
Affinity DataIC50: 3.10E+3nMAssay Description:A total of 30,000 chemical compounds (DiverSet Chemically Diverse Library and Combichem Library, ChemBridge Corp.) were screened for SrtA inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2009
Entry Details Article
PubMed
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