Compile Data Set for Download or QSAR
Report error Found 291 of affinity data for UniProtKB/TrEMBL: Q9Y5X5
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50029110(CHEMBL3361423)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human NPFF2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation by liquid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50029097(CHEMBL3361433)
Affinity DataEC50:  645nMAssay Description:Antagonist activity at human NPFF2 receptor expressed in CHO cells assessed as reversal of 1DMe-induced inhibition of intracellular cAMP accumulation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50029138(CHEMBL3360830)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at human NPFF2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2016
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50159227(CHEMBL3786309)
Affinity DataKd:  0.540nMAssay Description:Binding affinity to human NPFF2 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation spectrophotometric countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM86143(RFamide-related peptide 3 | L-Val-L-Pro-L-Asn-L-Le...)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50336912(Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...)
Affinity DataEC50:  379nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50060728((R)-5-(diaminomethyleneamino)-2-(2,2-diphenylaceta...)
Affinity DataEC50:  233nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50394975(CHEMBL2165921)
Affinity DataEC50:  1.66E+3nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50394976(CHEMBL2165922)
Affinity DataEC50:  298nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50394977(CHEMBL583068)
Affinity DataEC50:  1.19E+3nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50394978(CHEMBL573297)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50414848(CHEMBL572531)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human NPFF2 receptor expressed in cells assessed as beta-galactosidase levels after 5 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50394978(CHEMBL573297)
Affinity DataEC50:  1.26E+3nMAssay Description:Agonist activity at human NPFF2 receptor expressed in cells assessed as beta-galactosidase levels after 5 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50394977(CHEMBL583068)
Affinity DataEC50:  501nMAssay Description:Agonist activity at human NPFF2 receptor expressed in cells assessed as beta-galactosidase levels after 5 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50414849(CHEMBL572766)
Affinity DataEC50:  501nMAssay Description:Agonist activity at human NPFF2 receptor expressed in cells assessed as beta-galactosidase levels after 5 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50414850(CHEMBL575058)
Affinity DataEC50:  794nMAssay Description:Agonist activity at human NPFF2 receptor expressed in cells assessed as beta-galactosidase levels after 5 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50414851(CHEMBL574353)
Affinity DataEC50:  398nMAssay Description:Agonist activity at human NPFF2 receptor expressed in cells assessed as beta-galactosidase levels after 5 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50414852(CHEMBL573738)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human NPFF2 receptor expressed in cells assessed as beta-galactosidase levels after 5 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50414853(CHEMBL572825)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human NPFF2 receptor expressed in cells assessed as beta-galactosidase levels after 5 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50414854(CHEMBL574565)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human NPFF2 receptor expressed in cells assessed as beta-galactosidase levels after 5 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50414855(CHEMBL573518)
Affinity DataEC50:  158nMAssay Description:Agonist activity at human NPFF2 receptor expressed in cells assessed as beta-galactosidase levels after 5 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50414856(CHEMBL573519)
Affinity DataEC50:  126nMAssay Description:Agonist activity at human NPFF2 receptor expressed in cells assessed as beta-galactosidase levels after 5 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50508422(CHEMBL4442534)
Affinity DataEC50:  251nMAssay Description:Agonist activity at NPFF2 receptor (unknown origin) expressed in HEK293A cells assessed as inhibition of forskolin-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50508423(CHEMBL4449491)
Affinity DataEC50:  158nMAssay Description:Agonist activity at NPFF2 receptor (unknown origin) expressed in HEK293A cells assessed as inhibition of forskolin-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50508423(CHEMBL4449491)
Affinity DataEC50:  170nMAssay Description:Agonist activity at NPFF2 receptor (unknown origin) expressed in HEK293A cells assessed as inhibition of forskolin-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50508422(CHEMBL4442534)
Affinity DataEC50:  250nMAssay Description:Agonist activity at NPFF2 receptor (unknown origin) expressed in HEK293A cells assessed as inhibition of forskolin-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at NPFF2 receptor (unknown origin) expressed in HEK293A cells assessed as inhibition of forskolin-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKd:  0.370nMAssay Description:Binding affinity to human NPFFR2 expressed in green monkey COS-7 cell membranes by [125I]-1DMeNPFF radioligand based saturation binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cyclic cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50034115(1N-[1-carbamoyl-2-phenyl-(1S)-ethyl]-5-amino(imino...)
Affinity DataEC50:  517nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cyclic cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50037573((S)-2-[((S)-Pyrrolidine-2-carbonyl)-amino]-pentane...)
Affinity DataEC50:  309nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cyclic cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50565179(CHEMBL4782986)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS binding preincubated for 30 mins followed by [35S]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50565181(CHEMBL4783555)
Affinity DataEC50:  25nMAssay Description:Agonist activity at NPFFR2 (unknown origin) expressed in HEK-293A cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50555148(CHEMBL4745148)
Affinity DataEC50:  178nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 30 mins by LANCE ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50565182(CHEMBL4797394)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells by [35S]-GTP S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50565183(CHEMBL4790994)
Affinity DataEC50:  157nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells by [35S]-GTP S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50565185(CHEMBL4777535)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human NPFFR2 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50191288(CHEMBL3982697)
Affinity DataEC50:  794nMAssay Description:Agonist activity at NPFFR2 (unknown origin) expressed in mouse NIH3T3 cells by receptor selection and amplification technology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50565186(CHEMBL4785076)
Affinity DataEC50:  100nMAssay Description:Agonist activity at NPFFR2 (unknown origin) expressed in mouse NIH3T3 cells by receptor selection and amplification technology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50565188(CHEMBL4784123)
Affinity DataEC50:  794nMAssay Description:Agonist activity at NPFFR2 (unknown origin) expressed in mouse NIH3T3 cells by receptor selection and amplification technology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50565187(CHEMBL4794542)
Affinity DataEC50:  398nMAssay Description:Agonist activity at NPFFR2 (unknown origin) expressed in mouse NIH3T3 cells by receptor selection and amplification technology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50565186(CHEMBL4785076)
Affinity DataEC50:  3.16E+3nMAssay Description:Agonist activity at NPFFR2 (unknown origin) expressed in HEK293T cells harboring EP2 incubated for 15 mins by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50565188(CHEMBL4784123)
Affinity DataEC50:  6.31E+3nMAssay Description:Agonist activity at NPFFR2 (unknown origin) expressed in HEK293T cells harboring EP2 incubated for 15 mins by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50565187(CHEMBL4794542)
Affinity DataEC50:  3.98E+3nMAssay Description:Agonist activity at NPFFR2 (unknown origin) expressed in HEK293T cells harboring EP2 incubated for 15 mins by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50565189(CHEMBL4779743)
Affinity DataEC50:  1.47E+3nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cAMP production incubated for 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50565190(CHEMBL4800299)
Affinity DataEC50:  2.22E+3nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cAMP production incubated for 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50037557(2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4...)
Affinity DataKd:  0.210nMAssay Description:Binding affinity to human NPFFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50558724(CHEMBL4796596)
Affinity DataEC50:  311nMAssay Description:Agonist activity at NPFFR2 (unknown origin) expressed in HEK293-A cells assessed as reduction in forskolin-induced cAMP accumulation incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50558725(CHEMBL4790011)
Affinity DataEC50:  5.01E+3nMAssay Description:Agonist activity at NPFFR2 (unknown origin) expressed in HEK293-A cells assessed as reduction in forskolin-induced cAMP accumulation incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50558726(CHEMBL4784329)
Affinity DataEC50:  651nMAssay Description:Agonist activity at NPFFR2 (unknown origin) expressed in HEK293-A cells assessed as reduction in forskolin-induced cAMP accumulation incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
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