BDBM13505 Isothiazolidinone (IZD) deriv. 41::N-[(1S)-1-(1H-1,3-benzodiazol-2-yl)-2-[4-(1,1,3-trioxo-1,2-thiazolidin-5-yl)phenyl]ethyl]-3-[4-(trifluoromethyl)phenoxy]benzene-1-sulfonamide

SMILES FC(F)(F)c1ccc(Oc2cccc(c2)S(=O)(=O)N[C@@H](Cc2ccc(cc2)C2CC(=O)NS2(=O)=O)c2nc3ccccc3[nH]2)cc1

InChI Key InChIKey=PBMRAMLPCPANSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13505   

LigandPNGBDBM13505(N-[(1S)-1-(1H-1,3-benzodiazol-2-yl)-2-[4-(1,1,3-tr...)
Affinity DataIC50: 220nMAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair
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Date in BDB:
1/29/2007
Entry Details Article
PubMed