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TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50457513(CHEMBL4212908)
Affinity DataKd:  1.27E+5nMAssay Description:Binding affinity to 6His-tagged and human KDM4B tandem TUDOR domain (916 to 1030 residues) expressed in Escherichia coli BL21(DE3)-T1R by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataEC50:  3.00E+3nMAssay Description:Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50151923(CHEMBL3774537)
Affinity DataEC50:  1.00E+3nMAssay Description:Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513348(CHEMBL4585876)
Affinity DataEC50:  3.50E+3nMAssay Description:Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataEC50:  1.30E+3nMAssay Description:Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513346(CHEMBL4525269)
Affinity DataEC50:  9.10E+3nMAssay Description:Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataEC50:  2.00E+3nMAssay Description:Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513360(CHEMBL4573390)
Affinity DataEC50:  1.70E+3nMAssay Description:Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513361(CHEMBL4567766)
Affinity DataEC50:  1.40E+3nMAssay Description:Binding affinity to recombinant human N-terminal KDM4B (1 to 348 residues) fused upstream with E31G-R71G-K105E/ePL-tagged C-terminal transfected in H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50: 4nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50: 5nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50: 6nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50: 8nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50: 8nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50: 8nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50158844(CHEMBL3785491)
Affinity DataIC50: 10nMAssay Description:Inhibition of human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using H3K4me3 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50158844(CHEMBL3785491)
Affinity DataIC50: 10nMAssay Description:Inhibition of human KDM4B (1 to 500 residues) measured by antibody-based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50: 12nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50: 12nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513372(CHEMBL4440395)
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50153092(CHEMBL3775894)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513374(CHEMBL4466130)
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513352(CHEMBL4592908)
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513348(CHEMBL4585876)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513357(CHEMBL4590283)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50: 21nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50: 22nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513367(CHEMBL4559561)
Affinity DataIC50: 24nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513361(CHEMBL4567766)
Affinity DataIC50: 27nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50153093(CHEMBL3775668)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513360(CHEMBL4573390)
Affinity DataIC50: 29nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50151923(CHEMBL3774537)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50151923(CHEMBL3774537)
Affinity DataIC50: 31nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus-infected Sf9 cells using ARTKQTARK(Me3)STGGK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513344(CHEMBL4447515)
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513371(CHEMBL4438034)
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513349(CHEMBL4561958)
Affinity DataIC50: 33nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513351(CHEMBL4516101)
Affinity DataIC50: 33nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50598660(CHEMBL5203308)
Affinity DataIC50: 33nMAssay Description:Inhibition of KDM4B (unknown origin) measured by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM293660(3-({[(1S)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahyd...)
Affinity DataIC50: 35nMAssay Description:Inhibition of KDM4B (unknown origin) using H3K9me3 as substrate and measured by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50151919(CHEMBL3775121)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513345(CHEMBL4438830)
Affinity DataIC50: 36nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50: 36nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50151917(CHEMBL3775548)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50153161(CHEMBL3775545)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513346(CHEMBL4525269)
Affinity DataIC50: 40nMAssay Description:Inhibition of full length human KDM4B assessed as decrease in demethylation of substrate using peptide (ARTKQTARK(Me3)STGGKAPRKQLA-GGKbiotin) as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50151921(CHEMBL3774456)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513343(CHEMBL4449500)
Affinity DataIC50: 43nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513366(CHEMBL4435185)
Affinity DataIC50: 45nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513354(CHEMBL4558689)
Affinity DataIC50: 47nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50513362(CHEMBL4520178)
Affinity DataIC50: 49nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human KDM4B (1 to 500 residues) expressed in baculovirus infected Sf9 insect cells assessed as decrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
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