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TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM648432(US20240033256, Compound 7 | US20240033256, Compoun...)
Affinity DataEC50:  144nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM648433(US20240033256, Compound 8)
Affinity DataEC50:  304nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM648432(US20240033256, Compound 7 | US20240033256, Compoun...)
Affinity DataEC50:  44.4nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM648431(US20240033256, Compound 6)
Affinity DataEC50:  1.04E+3nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM648430(US20240033256, Compound 5)
Affinity DataEC50:  156nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM648429(US20240033256, Compound 4)
Affinity DataEC50:  13.3nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM648428(US20240033256, Compound 3)
Affinity DataEC50:  15.9nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM648427(US20240033256, Compound 2)
Affinity DataEC50:  15.3nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM648426(US20240033256, Compound 1)
Affinity DataEC50:  61.4nMAssay Description:Vero E6 cells (BCRC #60476, Bioresource Collection and Research Center, Hsinchu, Taiwan) were treated with one of Compounds 1-9 at a predetermined co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
Go to US Patent

TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50624690(CHEMBL5421176)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of ZIKV NS5 MTase activity assessed as methyltransferase reaction using capped RNA substrate pre-incubated for 2.5 hrs followed by enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50624688(CHEMBL5402544)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of ZIKV NS5 MTase activity assessed as methyltransferase reaction using capped RNA substrate pre-incubated for 2.5 hrs followed by enzyme ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506848(CHEMBL4556728)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of ZIKV NS5 MTase activity assessed as methyltransferase reaction using capped RNA substrate pre-incubated for 2.5 hrs followed by enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506842(CHEMBL3899268)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506858(CHEMBL4446745)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506850(CHEMBL3971531)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506853(CHEMBL3959384)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50624687(CHEMBL4206100)
Affinity DataIC50: 3.89E+4nMAssay Description:Inhibition of ZIKV NS5 MTase activity assessed as methyltransferase reaction using capped RNA substrate pre-incubated for 2.5 hrs followed by enzyme ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506841(CHEMBL4465538)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506843(CHEMBL3941938)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506855(CHEMBL4454666)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506849(CHEMBL3976785)
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506857(CHEMBL4522746)
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506847(CHEMBL4513879)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506852(CHEMBL4437452)
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506856(CHEMBL4547767)
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506845(CHEMBL4436568)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506851(CHEMBL4475329)
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50624689(CHEMBL5414044)
Affinity DataIC50: 1.83E+5nMAssay Description:Inhibition of ZIKV NS5 MTase activity assessed as methyltransferase reaction using capped RNA substrate pre-incubated for 2.5 hrs followed by enzyme ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506859(CHEMBL4522025)
Affinity DataIC50: 1.85E+5nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506854(CHEMBL3890313)
Affinity DataIC50: 2.21E+5nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506840(CHEMBL4538799)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506844(CHEMBL4578774)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGenome polyprotein(ZIKV)
National Health Research Institutes

US Patent
LigandPNGBDBM50506846(CHEMBL4436970)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of ZIKV 2'-O-MTase assessed as reduction in [3H]AdoMet transfer on to capped GpppAC4 RNA after 30 mins by microbeta liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed