29 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Tuning the Reactivity of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Activators for Optimal

Rigel Pharmaceuticals
Optimization of Pharmacokinetic and In Vitro Safety Profile of a Series of Pyridine Diamide Indirect AMPK Activators.

Rigel Pharmaceuticals
Optimization of Pyrimidine Compounds as Potent JAK1 Inhibitors and the Discovery of R507 as a Clinical Candidate.

Rigel Pharmaceuticals
Structure activity relationships leading to the identification of the indirect activator of AMPK, R419.

Rigel Pharmaceuticals
Bicyclic pyrimidine compounds as potent IRAK4 inhibitors.

Rigel Pharmaceuticals
Discovery of 5-Aryl-2,4-diaminopyrimidine Compounds as Potent and Selective IRAK4 Inhibitors.

Rigel Pharmaceuticals
Discovery of dual Axl/VEGF-R2 inhibitors as potential anti-angiogenic and anti-metastatic drugs for cancer chemotherapy.

Rigel Pharmaceuticals
Developing DYRK inhibitors derived from the meridianins as a means of increasing levels of NFAT in the nucleus.

Rigel Pharmaceuticals
GCN2 AND PERK KINASE INHIBITORS AND METHODS OF USE THEREOF

Deciphera Pharmaceuticals
Substituted piperazines as BTK inhibitors

Hutchison Medipharma
Fluoroalkyl-oxadiazoles and uses thereof

Tenaya Therapeutics
Heterocyclic compounds as immunomodulators

Incyte
Phosphonate linkers and their use to facilitate cellular retention of compounds

Merck Sharp & Dohme
Pyrazolo[1,5-a]pyrazin-4-yl derivatives

Pfizer
Cyclic di-nucleotide compounds as sting agonists

Merck Sharp & Dohme
Small molecule activators of Parkin enzyme function

Mayo Foundation For Medical Education and Research
Therapeutic compounds and uses thereof

Kala Pharmaceuticals
CRBN ligands and uses thereof

Kymera Therapeutics
Alpha-truxillic acid derivatives and pharmaceutical compositions thereof

The State University of New York
HDAC inhibitor compounds and methods of treatment

University of Florida Research Foundation
Pyridinecarboxamide derivatives, preparation method thereof and pharmaceutical uses thereof

Jiangsu Hengrui Medicine
JAK inhibitors containing a 4-membered heterocyclic amide

Theravance Biopharma R&D Ip
Spirocyclic sulfones as gamma secretase inhibitors

Merck Sharp & Dohme
6-substituted demethyl-estradiol derivatives as selective ER-β agonists

Endece
Pyrazolo[3,4-c]pyridine compounds and methods of use

Genetech
Triazolyl PDE10 inhibitors

Merck Sharp & Dohme
Synthesis, Biological Evaluation, and Docking of Dihydropyrazole Sulfonamide Containing 2-hydroxyphenyl Moiety: A Series of Novel MMP-2 Inhibitors.

Nanjing University
Pyrazolopyrimidine compounds and their use as PDE10 inhibitors

Mitsubishi Tanabe Pharma