31 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Virtual screening and experimental validation identify novel modulators of nuclear receptor RXRa from Drugbank database.
Xiamen University
Binding characterization, synthesis and biological evaluation of RXRa antagonists targeting the coactivator binding site.
Xiamen University
Synthesis and SAR study of modulators inhibiting tRXRa-dependent AKT activation.
Xiamen University
Fatty acids as natural specific inhibitors of the proto-oncogenic protein Shp2.
Xiamen University
Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration.
Xiamen University
Design, synthesis, and biological evaluation of novel 4,4'-bipyridine derivatives acting as CDK9-Cyclin T1 protein-protein interaction inhibitors against triple-negative breast cancer.
Xiamen University
Peptide Inhibitor Targeting the Extraterminal Domain in BRD4 Potently Suppresses Breast Cancer Both In Vitro and In Vivo.
Xiamen University
A CARM1 Inhibitor Potently Suppresses Breast Cancer Both In Vitro and In Vivo.
Xiamen University
A Molecular Toolbox of Positron Emission Tomography Tracers for General Anesthesia Mechanism Research.
Xiamen University
Discovery of bipyridine amide derivatives targeting pRXRα-PLK1 interaction for anticancer therapy.
Xiamen University
Inhibitory effects of phloridzin dihydrate on the activity of mushroom (Agaricus bisporus) tyrosinase.
Xiamen University
Discovery of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carboxamide derivatives as novel anti-cancer agents targeting Nur77.
Xiamen University
Design, synthesis, and biological evaluation of novel sulindac derivatives as partial agonists of PPARγ with potential anti-diabetic efficacy.
Xiamen University
Optimization of novel oxidative DIMs as Nur77 modulators of the Nur77-Bcl-2 apoptotic pathway.
Xiamen University
Discovery of methyl 3-((2-((1-(dimethylglycyl)-5-methoxyindolin-6-yl)amino)-5-(trifluoro-methyl) pyrimidin-4-yl)amino)thiophene-2-carboxylate as a potent and selective polo-like kinase 1 (PLK1) inhibitor for combating hepatocellular carcinoma.
Xiamen University
Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators.
Xiamen University
Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant.
Xiamen University
Discovery and optimization of 4-oxo-2-thioxo-thiazolidinones as NOD-like receptor (NLR) family, pyrin domain-containing protein 3 (NLRP3) inhibitors.
Xiamen University
Design, synthesis and biological evaluation of tetrazole-containing RXRα ligands as anticancer agents.
Xiamen University
SAR study of celastrol analogs targeting Nur77-mediated inflammatory pathway.
Xiamen University
Cytotoxic Components from Hypericum elodeoides Targeting RXRα and Inducing HeLa Cell Apoptosis through Caspase-8 Activation and PARP Cleavage.
Xiamen University
Identification of a New RXRα Antagonist Targeting the Coregulator-Binding Site.
Xiamen University
Synthesis and antityrosinase activities of alkyl 3,4-dihydroxybenzoates.
Xiamen University
