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BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 708K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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7 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
An update on therapeutic opportunities offered by cancer glycolytic metabolism.EBI
University of Pisa
Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3.EBI
Astrazeneca
Targeting the Warburg Effect in cancer; relationships for 2-arylpyridazinones as inhibitors of the key glycolytic enzyme 6-phosphofructo-2-kinase/2,6-bisphosphatase 3 (PFKFB3).EBI
University of Auckland
Discovery of a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR).EBI
Exelixis
PFKFB3 inhibitors as potential anticancer agents: Mechanisms of action, current developments, and structure-activity relationships.EBI
Liaocheng University
Synthesis of amide and sulfonamide substituted N-aryl 6-aminoquinoxalines as PFKFB3 inhibitors with improved physicochemical properties.EBI
Selvita
Thiazolidine-diones. Biochemical and biological activity of a novel class of tyrosine protein kinase inhibitors.BDB
Ciba-Geigy