68 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C.
Griffith University
Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII.
Uppsala University
Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters.
Universita Degli Studi Di Firenze
Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases.
Griffith University
Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I-XIV.
TBA
Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX.
Vilnius University
Natural product hybrid and its superacid synthesized analogues: dodoneine and its derivatives show selective inhibition of carbonic anhydrase isoforms I, III, XIII and XIV.
Superacid Group In Organic Synthesis Team-Universit£
4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII.
Vilnius University Institute of Biotechnology
Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases.
Universidad Nacional De La Plata
Tricyclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibita- andß-carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms.
University of Pisa
Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins.
University of Cagliari
Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases.
Vilnius University
Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV.
Universita Degli Studi Di Firenze
Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors.
University of Florida
Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV.
Istituto Di Biostrutture E Bioimmagini-Cnr
Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids.
Universita Degli Studi Di Firenze
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins.
Universita Degli Studi Di Firenze
The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors.
Universita Degli Studi Di Firenze
Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions.
Universita Degli Studi Di Firenze
A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases.
Universita Degli Studi Di Firenze
Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors.
Istituto Di Biostrutture E Bioimmagini-Cnr
Carbonic anhydrases as targets for medicinal chemistry.
Universita Degli Studi Di Firenze
Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I.
Universita Degli Studi Di Firenze
Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.
Universita Degli Studi Di Firenze
Carbonic anhydrase inhibitors. Inhibition of the newly isolated murine isozyme XIII with anions.
Universita Degli Studi Di Firenze
Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design.
University of Tampere
New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II.
Universita Degli Studi Di Firenze
Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against humana- and bacterial/fungalß-carbonic anhydrases.
Ecole Nationale Sup£Rieure De Chimie De Montpellier
Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.
Universita Degli Studi Di Firenze
Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms.
University of Florida
Indapamide-like benzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, and XIII.
Institute of Biotechnology
4-[N-(substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII.
Vilnius University
Paraoxon, 4-nitrophenyl phosphate and acetate are substrates ofa- but not ofß-,¿- and¿-carbonic anhydrases.
Università
Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule.
Universita Degli Studi Di Firenze
The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
University of Tampere and Tampere University Hospital
Investigations of the esterase, phosphatase, and sulfatase activities of the cytosolic mammalian carbonic anhydrase isoforms I, II, and XIII with 4-nitrophenyl esters as substrates.
Universita Degli Studi Di Firenze
Developments of small molecules as inhibitors for carbonic anhydrase isoforms.
Georgia State University
Inhibition of Carbonic Anhydrase Using SLC-149: Support for a Noncatalytic Function of CAIX in Breast Cancer.
University of Florida
Optimization of Acetazolamide-Based Scaffold as Potent Inhibitors of Vancomycin-Resistant
Purdue University
3-Functionalised benzenesulphonamide based 1,3,4-oxadiazoles as selective carbonic anhydrase XIII inhibitors: Design, synthesis and biological evaluation.
National Institute of Pharmaceutical Education and Research (NIPER)
Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors.
University of Florence
Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects.
University of Florence
Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.
Vilnius University
Pyrrolidinone-bearing methylated and halogenated benzenesulfonamides as inhibitors of carbonic anhydrases.
Kaunas University of Technology
Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies.
Universita Degli Studi Di Firenze
Inhibition of human carbonic anhydrase isoforms I-XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties.
Universita Degli Studi Di Firenze
Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII.
Vilnius University
Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.
University of Florida
Benzimidazole design, synthesis, and docking to build selective carbonic anhydrase VA inhibitors.
Vilnius University
Design of two-tail compounds with rotationally fixed benzenesulfonamide ring as inhibitors of carbonic anhydrases.
Vilnius University
Introduction of Intrinsic Kinetics of Protein-Ligand Interactions and Their Implications for Drug Design.
Vilnius University
Substituted 2-azabicycles and their use as orexin receptor modulators
Janssen Pharmaceutica
Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives.
Chinese Academy of Sciences