BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 708K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

13 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
It's ok to be outnumbered - sub-stoichiometric modulation of homomeric protein complexes.EBI
Genentech
Agonist Lock Touched and Untouched Retinoic Acid Receptor-Related Orphan Receptor-γt (RORγt) Inverse Agonists: Classification Based on the Molecular Mechanisms of Action.EBI
Fudan University
Discovery of an Oral, Rule of 5 Compliant, Interleukin 17A Protein-Protein Interaction Modulator for the Potential Treatment of Psoriasis and Other Inflammatory Diseases.EBI
Leo Pharma Research & Early Development
Multicomponent Macrocyclic IL-17a Modifier.EBI
University of Groningen
Targeting Bromodomain-Selective Inhibitors of BET Proteins in Drug Discovery and Development.EBI
Sichuan University
Novel Difluorocyclohexyl Derivatives as IL-17 Modulators for Treating Inflammatory and Autoimmune Diseases.EBI
Smith, Gambrell & Russell
Macrolide Inspired Macrocycles as Modulators of the IL-17A/IL-17RA Interaction.EBI
Fidelta
Novel Difluorocyclohexyl Derivatives as IL-17 Modulators for Treating Inflammatory and Autoimmune Diseases.EBI
Smith, Gambrell & Russell
Imidazo[1,2-EBI
Smith, Gambrell & Russell
Interleukin-17A Peptide Aptamers with an Unexpected Binding Moiety Selected by cDNA Display under Heterogenous Conditions.EBI
Saitama University
Substituted cinnolines as inhibitors of LRRK2 kinase activityBDB
Imago Pharmaceuticals
Pyrimidone derivativesBDB
Mitsubishi Tanabe Pharma
Inhibition of AMP deaminase activity does not improve glucose control in rodent models of insulin resistance or diabetes.BDB
Astrazeneca R&D