27 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Recent Update on Human Lactate Dehydrogenase Enzyme 5 (hLDH5) Inhibitors: A Promising Approach for Cancer Chemotherapy.
National Cancer Institute-Cro
An update on therapeutic opportunities offered by cancer glycolytic metabolism.
University of Pisa
Optimization of 5-(2,6-dichlorophenyl)-3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase.
Genentech
Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase.
Genentech
Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenase.
Genentech
Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase.
Genentech
Discovery of the First Lactate Dehydrogenase Proteolysis Targeting Chimera Degrader for the Treatment of Pancreatic Cancer.
Icahn School of Medicine At Mount Sinai
Structure-based optimization of hydroxylactam as potent, cell-active inhibitors of lactate dehydrogenase.
Genentech
New salicylic acid derivatives, double inhibitors of glycolate oxidase and lactate dehydrogenase, as effective agents decreasing oxalate production.
Universidad De Granada
Discovery of novel human lactate dehydrogenase inhibitors: Structure-based virtual screening studies and biological assessment.
Sapienza University of Rome
Optimization of ether and aniline based inhibitors of lactate dehydrogenase.
Vanderbilt University
Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice.
Genentech
Interrogating the Lactate Dehydrogenase Tetramerization Site Using (Stapled) Peptides.
University of Louvain
Selective inhibitors of human lactate dehydrogenases and lactate dehydrogenase from the malarial parasite Plasmodium falciparum.
University of New Mexico School of Medicine
Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH).
National Center For Advancing Translational Sciences
Cardiac glycoside analogs and their use in methods for inhibition of viral infection
The John Hopkins University
Substituted N-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase BTK inhibitors
University of Utah
Synthesis and biological evaluation of some new N(4)-substituted isatin-3-thiosemicarbazones.
Bahauddin Zakariya University
Novel behavior of O-methylated beta-cyclodextrins in inclusion of meso-tetraarylporphyrins.
Doshisha University