28 articles for thisTarget
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In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor.

Glaxosmithkline
The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules.

University of Manitoba
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.

University of California
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.

Institute of Anatomy of The Bayerische Julius-Maximilians-Universit£T
Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney.

Tokyo University of Science
Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.

Kyoto University Hospital
Functional characterization of mouse cation transporter mOCT2 compared with mOCT1.

Kyushu University
Interactions of n-tetraalkylammonium compounds and biguanides with a human renal organic cation transporter (hOCT2).

University of California
Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3.

University of Bonn
Selective substrates for non-neuronal monoamine transporters.

University of Heidelberg
Transport of monoamine transmitters by the organic cation transporter type 2, OCT2.

University of Heidelberg
A transfected cell model for the renal toxin transporter, rOCT2.

University of Texas M. D. Anderson Cancer Center
Human neurons express the polyspecific cation transporter hOCT2, which translocates monoamine neurotransmitters, amantadine, and memantine.

Institut F£R Physiologie
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.

Kyoto University Hospital
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.

Kyoto University Hospital
Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

University of California San Francisco
Different transport properties between famotidine and cimetidine by human renal organic ion transporters (SLC22A).

Kyoto University Hospital
Selective Inhibition of Organic Cation Transporter 1 by Benzoylpaeoniflorin Attenuates Hepatic Lipid Accumulation through AMPK Activation.

Tianjin University
Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting.

Pfizer
Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain.

Medical College of Georgia
Cloning and characterization of two human polyspecific organic cation transporters.

Anatomisches Institut Der Bayerischen Julius-Maximilians-Universit£T
A new chemotype inhibitor for the human organic cation transporter 3 (hOCT3).

Virginia Commonwealth University
Synthesis of peptide borate ester compound and use thereof

Jiangsu Chia Tai Fenghai Pharmaceutical
Benzimidazole derivatives as RLK and ITK inhibitors

Principia Biopharma
Optically active diazabicyclooctane derivatives and process for preparing the same

Meiji Seika Pharma
Orally available viridiofungin derivative possessing anti-HCV activity

Chugai Seiyaku Kabushiki Kaisha
A new screening assay for allosteric inhibitors of cSrc.

Chemical Genomics Centre of The Max Planck Society