19 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
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Article Title
Organization
Small molecule inhibitors targeting activator protein 1 (AP-1).
University of Texas Medical Branch
Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity.
National Defense Medical Center, Taiwan
Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition.
National Cancer Institute-Frederick
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
University of Oxford
Grassypeptolides F and G, cyanobacterial peptides from Lyngbya majuscula.
National Cancer Institute-Frederick
Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii.
Nci-Frederick
Design, synthesis, and structure-activity relationship studies of thiophene-3-carboxamide derivatives as dual inhibitors of the c-Jun N-terminal kinase.
Sanford-Burnham Medical Research Institute
Inhibitors of the oncogenic transcription factor AP-1 from Podocarpus latifolius.
National Cancer Institute-Frederick
Synthesis and SAR of novel quinazolines as potent and brain-penetrant c-jun N-terminal kinase (JNK) inhibitors.
The Scripps Research Institute
Synthesis and evaluation of quinazolinone derivatives as inhibitors of NF-kappaB, AP-1 mediated transcription and eIF-4E mediated translational activation: inhibitors of multi-pathways involve in cancer.
B.V. Patel Pharmaceutical Education and Research Development Centre
Surveying polypeptide and protein domain conformation and association with FlAsH and ReAsH.
Yale University
Design, synthesis and evaluation of novel 2-thiophen-5-yl-3H-quinazolin-4-one analogues as inhibitors of transcription factors NF-kappaB and AP-1 mediated transcriptional activation: Their possible utilization as anti-inflammatory and anti-cancer agents.
B.V. Patel Pharmaceutical Education and Research Development Centre
Design, synthesis and characterization of novel 2-(2,4-disubstituted-thiazole-5-yl)-3-aryl-3H-quinazoline-4-one derivatives as inhibitors of NF-kappaB and AP-1 mediated transcription activation and as potential anti-inflammatory agents.
B.V. Patel Pharmaceutical Education and Research Development Centre
Structure-activity studies of phenanthroindolizidine alkaloids as potential antitumor agents.
Yale University
Synthesis and SAR of aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors.
Ucb Pharma
Hemodynamic effects of potent and selective JNK inhibitors in anesthetized rats: implication for targeting protein kinases in metabolic diseases.
Abbott Laboratories
Inhibitors of NF-kappaB and AP-1 gene expression: SAR studies on the pyrimidine portion of 2-chloro-4-trifluoromethylpyrimidine-5-[N-(3', 5'-bis(trifluoromethyl)phenyl)carboxamide].
Signal Pharmaceuticals
Melonoside B and Melonosins A and B, Lipids Containing Multifunctionalized ω-Hydroxy Fatty Acid Amides from the Far Eastern Marine Sponge Melonanchora kobjakovae.
Far Eastern Branch of The Russian Academy of Sciences
