26 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
Organization
Oxaspirol B with p97 Inhibitory Activity and Other Oxaspirols from Lecythophora sp. FL1375 and FL1031, Endolichenic Fungi Inhabiting Parmotrema tinctorum and Cladonia evansii.
University of Arizona
Structure-Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97.
University of Pittsburgh
Discovery of 2-(cyclohexylmethylamino)pyrimidines as a new class of reversible valosine containing protein inhibitors.
Nerviano Medical Sciences
Alkylsulfanyl-1,2,4-triazoles, a new class of allosteric valosine containing protein inhibitors. Synthesis and structure-activity relationships.
TBA
2-Anilino-4-aryl-1,3-thiazole inhibitors of valosin-containing protein (VCP or p97).
Kyowa Hakko Kogyo
Optimization of 1,2,4-Triazole-Based p97 Inhibitors for the Treatment of Cancer.
University of Pittsburgh Chemical Diversity Center
Synthesis and structure-activity relationships of N - (3 - (1H-imidazol-2-yl) phenyl) - 3-phenylpropionamide derivatives as a novel class of covalent inhibitors of p97/VCP ATPase.
Chinese Academy of Medical Sciences and Peking Union Medical College
The Emerging Landscape of Small-Molecule Therapeutics for the Treatment of Huntington's Disease.
Aligarh Muslim University
Discovery of a new class of valosine containing protein (VCP/P97) inhibitors for the treatment of colorectal cancer.
Nanjing Normal University
AAA ATPases as therapeutic targets: Structure, functions, and small-molecule inhibitors.
California Institute of Technology
Discovery of novel pyrimidine molecules containing boronic acid as VCP/p97 Inhibitors.
Nanjing Normal University
A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells.
California Institute of Technology
Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway.
University of Pittsburgh
p97: An Emerging Target for Cancer, Neurodegenerative Diseases, and Viral Infections.
TBA
Discovery of a new class of valosine containing protein (VCP/P97) inhibitors for the treatment of non-small cell lung cancer.
Nanjing Normal University
Discovery of a First-in-Class, Potent, Selective, and Orally Bioavailable Inhibitor of the p97 AAA ATPase (CB-5083).
Cleave Biosciences
Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97.
University of Pittsburgh Chemical Diversity Center
ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4A.
University of Arizona
Organosilicon carriers for use in treating infections and/or diseases caused by SARS viruses
Individual
Substituted 2-phenyl (AZA)benzofuran compounds for the treatment of hepatitis C
Bristol-Myers Squibb
Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin