The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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23 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of novel BCL6-Targeting PROTACs with effective antitumor activities against DLBCL in vitro and in vivo.EBI
East China Normal University
Facilitating the development of molecular glues: Opportunities from serendipity and rational design.EBI
Sichuan University
Discovery of an EBI
TBA
Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 EBI
The Institute of Cancer Research
B-cell Lymphoma 6 Inhibitors: Current Advances and Prospects of Drug Development for Diffuse Large B-cell Lymphomas.EBI
East China Normal University
Optimizing Shape Complementarity Enables the Discovery of Potent Tricyclic BCL6 Inhibitors.EBI
The Institute of Cancer Research
Into Deep Water: Optimizing BCL6 Inhibitors by Growing into a Solvated Pocket.EBI
TBA
Monomeric Targeted Protein Degraders.EBI
TBA
Rationally Designed Covalent BCL6 Inhibitor That Targets a Tyrosine Residue in the Homodimer Interface.EBI
Dana-Farber Cancer Institute
Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of EBI
East China Normal University and Shanghai Fengxian District Central Hospital Joint Center For Translational Medicine
Achieving EBI
TBA
Free Ligand 1D NMR Conformational Signatures To Enhance Structure Based Drug Design of a Mcl-1 Inhibitor (AZD5991) and Other Synthetic Macrocycles.EBI
Astrazeneca
Progress toward B-Cell Lymphoma 6 BTB Domain Inhibitors for the Treatment of Diffuse Large B-Cell Lymphoma and Beyond.EBI
University of Maryland
A genetically selected cyclic peptide inhibitor of BCL6 homodimerization.EBI
University of Southampton
Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.EBI
University of Maryland
Discovery of a B-Cell Lymphoma 6 Protein-Protein Interaction Inhibitor by a Biophysics-Driven Fragment-Based Approach.EBI
Takeda Pharmaceutical
Discovery of a novel B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor by utilizing structure-based drug design.EBI
Takeda Pharmaceutical
X-ray Structures of Target-Ligand Complexes Containing Compounds with Assay Interference Potential.EBI
Rheinische Friedrich-Wilhelms-Universit£T
Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors.EBI
Astrazeneca
AMINO ACID BASED CARBAMATES AND/OR UREAS FOR THE TREATMENT OF SORTILIN DEPENDENT DISEASESBDB
Vesper Bio
NOVEL COMPOUNDS AND THEIR USEBDB
Debiopharm International
Treatment of autism spectrum disorders, obsessive-compulsive disorder and anxiety disordersBDB
Rugen Holdings (Cayman)
Aminocyclobutanes as monoacylglycerol lipase modulatorsBDB
Janssen Pharmaceutica