BDBM15163 3-(4-{[4-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)piperidin-1-yl]methyl}phenyl)-2-phenylquinoxaline-6-carboxylic acid::quinoxaline 16b

SMILES OC(=O)c1ccc2nc(-c3ccccc3)c(nc2c1)-c1ccc(CN2CCC(CC2)n2c3ccccc3[nH]c2=O)cc1

InChI Key InChIKey=DNNVPDHNAOWAES-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 15163   

LigandPNGBDBM15163(3-(4-{[4-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-y...)
Affinity DataIC50: 166nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM15163(3-(4-{[4-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-y...)
Affinity DataIC50: 166nMAssay Description:Inhibition of AktMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM15163(3-(4-{[4-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-y...)
Affinity DataIC50: 166nMpH: 7.5 T: 2°CAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandPNGBDBM15163(3-(4-{[4-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-y...)
Affinity DataIC50: 388nMAssay Description:Inhibition of Akt2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM15163(3-(4-{[4-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-y...)
Affinity DataIC50: 388nMAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
LigandPNGBDBM15163(3-(4-{[4-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-y...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Akt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM15163(3-(4-{[4-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-y...)
Affinity DataIC50: 3.20E+3nMAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM15163(3-(4-{[4-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-y...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed