BDBM163679 3,4‐Dichloro‐1‐benzothiophene‐2‐carbohydrazide (08)

SMILES NNC(=O)c1sc2cccc(Cl)c2c1Cl

InChI Key InChIKey=HSSHUDKWJRJKPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 163679   

TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163679(3,4‐Dichloro‐1‐benzothiophene...)
Affinity DataIC50: 220nMAssay Description:Gel-based assays were performed by combining 4 µL of OGG1 (62.5 nM) with 1 µL of inhibitor or buffer. Substrate (5 µL, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163679(3,4‐Dichloro‐1‐benzothiophene...)
Affinity DataIC50: 350nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed