BDBM163682 4‐Bromo‐N'‐cyclohexylidenebenzohydrazide (0151)

SMILES Brc1ccc(cc1)-[#6](=O)-[#7]\[#7]=[#6]-1/[#6]-[#6]-[#6]-[#6]-[#6]-1

InChI Key InChIKey=JQYAVADPMXAFEZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 163682   

TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163682(4‐Bromo‐N'‐cyclohexylidenebe...)
Affinity DataIC50: 630nMAssay Description:Gel-based assays were performed by combining 4 µL of OGG1 (62.5 nM) with 1 µL of inhibitor or buffer. Substrate (5 µL, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163682(4‐Bromo‐N'‐cyclohexylidenebe...)
Affinity DataIC50: 610nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed