BDBM163683 N'‐Cyclohexylidene‐3‐hydroxynaphthalene‐2‐carbohydrazide (0158)

SMILES [#8]-c1cc2ccccc2cc1-[#6](=O)-[#7]\[#7]=[#6]-1/[#6]-[#6]-[#6]-[#6]-[#6]-1

InChI Key InChIKey=HNMGRBCUJRVTQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 163683   

TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163683(N'‐Cyclohexylidene‐3‐hydroxy...)
Affinity DataIC50: 340nMAssay Description:Gel-based assays were performed by combining 4 µL of OGG1 (62.5 nM) with 1 µL of inhibitor or buffer. Substrate (5 µL, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163683(N'‐Cyclohexylidene‐3‐hydroxy...)
Affinity DataIC50: 290nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed