BDBM166636 7-[(4-Chlorobenzyl)oxy]-3,4-dihydronaphthalen-1(2H)-one (4g)

SMILES Clc1ccc(COc2ccc3CCCC(=O)c3c2)cc1

InChI Key InChIKey=HLUBOHGJNPWDGC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 166636   

TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166636(7-[(4-Chlorobenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 33nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166636(7-[(4-Chlorobenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 4.10nMAssay Description:IC50 values for the inhibition of MAO-A and MAO-B were determined using the recombinant human enzymes as enzyme sources, and kynuramine as non-select...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM166636(7-[(4-Chlorobenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human MAO-A assessed as measuring amount of 4-hydroxyquinoline using kynuramine as substrate incubated for 20 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM166636(7-[(4-Chlorobenzyl)oxy]-3,4-dihydronaphthalen-1(2H...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human MAO-B assessed as measuring amount of 4-hydroxyquinoline using kynuramine as substrate incubated for 20 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed