BDBM27514 13-amino-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaen-8-one::indeno[1,2-c]isoquinolinone, 2a

SMILES Nc1ccc2Cc3c([nH]c(=O)c4ccccc34)-c2c1

InChI Key InChIKey=LQEYAIKMIJUZNT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27514   

TargetPoly [ADP-ribose] polymerase 1(Human)
Inotek Pharmaceuticals

LigandPNGBDBM27514(13-amino-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...)
Affinity DataIC50: 300nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed