BDBM27529 13-fluoro-N-(morpholin-4-yl)-8-oxo-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(10),2(7),3,5,11(16),12,14-heptaene-14-sulfonamide::indeno[1,2-c]isoquinolinone, 12b

SMILES Fc1cc-2c(Cc3c-2[nH]c(=O)c2ccccc32)cc1S(=O)(=O)NN1CCOCC1

InChI Key InChIKey=WOMLRJQZCAFUSQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27529   

TargetPoly [ADP-ribose] polymerase 1(Human)
Inotek Pharmaceuticals

LigandPNGBDBM27529(13-fluoro-N-(morpholin-4-yl)-8-oxo-9-azatetracyclo...)
Affinity DataIC50: 450nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed