BDBM4441 (4S,5S)-2,7-bis({[2-(1-benzofuran-2-yl)phenyl]methyl})-4,5-dihydroxy-1,2,7-thiadiazepane-1,1-dione::cyclic sulfamide, biphenyl analog 28

SMILES O[C@H]1CN(Cc2ccccc2-c2cc3ccccc3o2)S(=O)(=O)N(Cc2ccccc2-c2cc3ccccc3o2)C[C@@H]1O

InChI Key InChIKey=NIBXFUBAUTVIGY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4441   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4441((4S,5S)-2,7-bis({[2-(1-benzofuran-2-yl)phenyl]meth...)
Affinity DataKi:  530nM ΔG°:  -8.70kcal/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM4441((4S,5S)-2,7-bis({[2-(1-benzofuran-2-yl)phenyl]meth...)
Affinity DataKi:  530nMAssay Description:Binding affinity to wild-type HIV1 protease expressed in Escherichia coli by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed