BDBM50211201 CHEMBL3945453

SMILES C1N=C(Nc2ncc(s2)-c2ccccc2)OC11CN2CCC1CC2

InChI Key

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50211201   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211201(CHEMBL3945453)
Affinity DataEC50:  400nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in HEK293 cells co-expressing human RIC3 measured for 2 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50211201(CHEMBL3945453)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human 5-HT3A expressed in HEK293 cells assessed as reduction in acetylcholine-induced activity preincubated for 30 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed