BDBM50524579 CHEMBL4531859::US10980809, Example 23

SMILES COc1cccc(NC(=O)Nc2ccc(Oc3ncnc4cc(OC)c5OCCOc5c34)cc2)c1

InChI Key InChIKey=OAICBADCKDBOKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524579   

TargetVascular endothelial growth factor receptor 2(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50524579(CHEMBL4531859 | US10980809, Example 23)
Affinity DataIC50: 4nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system using Ulight-JA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50524579(CHEMBL4531859 | US10980809, Example 23)
Affinity DataIC50: 50nMAssay Description:1. Dilution of the compound: a total of 12 concentrations were obtained using a 4-fold gradient dilution from the highest concentration of 10000 nM (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent