BDBM50524582 CHEMBL4461971::US10980809, Example 73

SMILES Fc1ccc(cc1NC(=O)Nc1ccc(Oc2ncnc3cc(OCCN4CCOCC4)c4OCCOc4c23)cc1)C(F)(F)F

InChI Key InChIKey=DYGCGFFVCYAIFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524582   

TargetVascular endothelial growth factor receptor 2(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50524582(CHEMBL4461971 | US10980809, Example 73)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system using Ulight-JA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50524582(CHEMBL4461971 | US10980809, Example 73)
Affinity DataIC50: 2.75E+3nMAssay Description:1. Dilution of the compound: a total of 12 concentrations were obtained using a 4-fold gradient dilution from the highest concentration of 10000 nM (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent