BDBM50607669 CHEMBL5219933::US20240239774, Example 47

SMILES COC(=O)c1cccc(Cc2cn(C)nc2-c2cc(Cl)nc(N)n2)c1

InChI Key InChIKey=AYWBCMQVIQTKRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607669   

TargetAdenylate cyclase type 10(Human)
Cornell University

US Patent
LigandPNGBDBM50607669(CHEMBL5219933 | US20240239774, Example 47)
Affinity DataIC50: 70nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University

US Patent
LigandPNGBDBM50607669(CHEMBL5219933 | US20240239774, Example 47)
Affinity DataIC50: 436nMAssay Description:Inhibition of human ADCY10 assessed as cAMP accumulation preincubated for 15 mins followed by substrate addition using alpha-32P labelled ATP as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed