BDBM552453 WO2022098807, Example 1-5

SMILES Cc1c2NCCOc2ncc1-c1ccc2cnc(Nc3cnn(C)c3)nc2c1

InChI Key InChIKey=KHYRHPHKPHPXSM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552453   

LigandPNGBDBM552453(WO2022098807, Example 1-5)
Affinity DataIC50: 0.710nMAssay Description:HPK1-Catalytic domain enzyme is preincubated for 30 minutes with varying concentrations of investigational test compounds, or DMSO reference. HPK1 ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022098807