BDBM552464 WO2022098807, Example 2-8

SMILES Cc1c2NCCOc2ncc1-c1cc2nc(Nc3cnn(c3)C3(C)CC3)ncc2c(N)c1F

InChI Key InChIKey=ACAZCESHNUGFOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552464   

LigandPNGBDBM552464(WO2022098807, Example 2-8)
Affinity DataIC50: 0.0900nMAssay Description:HPK1-Catalytic domain enzyme is preincubated for 30 minutes with varying concentrations of investigational test compounds, or DMSO reference. HPK1 ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022098807