BDBM552502 WO2022098807, Example 2-46

SMILES Cc1c2NCCOc2ncc1-c1cc2nc(Nc3cnn(c3)C34CC(C3)(C4)C(C)(C)O)ncc2c(N)c1F

InChI Key InChIKey=XVDSDABBRKHSTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552502   

LigandPNGBDBM552502(WO2022098807, Example 2-46)
Affinity DataIC50: 0.0500nMAssay Description:HPK1-Catalytic domain enzyme is preincubated for 30 minutes with varying concentrations of investigational test compounds, or DMSO reference. HPK1 ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022098807