BDBM552503 WO2022098807, Example 2-47

SMILES CN1CC[C@@H](C1)n1cc(Nc2ncc3c(N)c(F)c(c(Cl)c3n2)-c2cnc3OCCNc3c2C)cn1

InChI Key InChIKey=PFUSMVAFWIOEIJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552503   

LigandPNGBDBM552503(WO2022098807, Example 2-47)
Affinity DataIC50: 0.180nMAssay Description:HPK1-Catalytic domain enzyme is preincubated for 30 minutes with varying concentrations of investigational test compounds, or DMSO reference. HPK1 ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022098807