BDBM636515 US20230365558, Compound 36

SMILES O[C@@H](CNC(=O)c1ccc2O[C@@]3(CCOC3)C(=O)Nc2c1)CN1CCc2ccccc2C1

InChI Key InChIKey=HAPNOVZTHHZJBV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636515   

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandPNGBDBM636515(US20230365558, Compound 36)
Affinity DataIC50: 7nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent