BDBM636525 US20230365558, Compound 47

SMILES COc1cc2OC3(CC3)C(=O)Nc2cc1C(=O)NC[C@H](O)CN1CCc2ccccc2C1

InChI Key InChIKey=KGHMYCQWPYRYGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 636525   

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandPNGBDBM636525(US20230365558, Compound 47)
Affinity DataIC50: 42nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent