BDBM8585 (3-Pyridylmethylene)tetrahydronaphthalene 3b::3-[(1Z)-1,2,3,4-tetrahydronaphthalen-1-ylidenemethyl]pyridine::3-[(Z)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]pyridine Hydrochloride

SMILES C1C\C(=C\c2cccnc2)c2ccccc2C1

InChI Key InChIKey=GCIGECZMYPPCHH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8585   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8585(3-[(Z)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]p...)
Affinity DataIC50: 141nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8585(3-[(Z)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]p...)
Affinity DataIC50: 1.42E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8585(3-[(Z)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]p...)
Affinity DataIC50: 3.79E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8585(3-[(Z)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]p...)
Affinity DataIC50: 3.79E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed