Compile Data Set for Download or QSAR
Report error Found 791 Enz. Inhib. hit(s) with Target = 'Interleukin-2'
TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50021400(CHEBI:74020 | DISOGLUSIDE)
Affinity DataKd:  0.0290nMAssay Description:Binding affinity to IL-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649497(US11891386, Compound ARI-083)
Affinity DataIC50: 0.300nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649500(US11891386, Compound ARI-120)
Affinity DataIC50: 0.300nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50579802(CHEMBL5081901)
Affinity DataEC50:  0.609nMAssay Description:Induction of stability of human recombinant interleukin 2 assessed as increase in mouse CTLL-2 cell proliferation measured after 48 hrs by WST-1 assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
LigandPNGBDBM784720(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Leu-Yme-Nal-Aib-Asp(...)
Affinity DataIC50: 0.630nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784722(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Ala-Yme-Nal-Aib-Asp(...)
Affinity DataIC50: 0.690nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784784(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Ala-Yme-Nal-Thp-Asp(...)
Affinity DataIC50: 0.780nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649499(US11891386, Compound ARI-118)
Affinity DataIC50: 0.800nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

LigandPNGBDBM784778(D-Lys(Ac)(@1)-Arg-Thr-Trp-Gln-Ala-Yme-Nal-Aib-Asp(...)
Affinity DataIC50: 0.960nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784746(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Yme-Nal-Aib-Asp(...)
Affinity DataIC50: 1.04nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784755(D-Lys(Ac)(@1)-Asn-Thr-Wme-Gln-Arg-Yme-Nal-Mle-Asp(...)
Affinity DataIC50: 1.21nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784780(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Ala-Yme-Nal-Arg-Asp(...)
Affinity DataIC50: 1.34nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784779(D-Lys(Ac)(@1)-Asn-Arg-Trp-Gln-Ala-Yme-Nal-Aib-Asp(...)
Affinity DataIC50: 1.38nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784776(Ahx(@1)-Asn-Thr-Trp-Gln-Ala-Yme-Nal-Aib-Asp(@1)-As...)
Affinity DataIC50: 1.44nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784772(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Agb-Yme-Nal-Aib-Asp(...)
Affinity DataIC50: 1.46nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784774(Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Yme-Nal-Thp-Asp(@1...)
Affinity DataIC50: 1.47nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784729(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Yme-Nal-Aib-Asp(...)
Affinity DataIC50: 1.55nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784733(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Tyr-Nal-Aib-Asp(...)
Affinity DataIC50: 1.59nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
TargetInterleukin-23 receptor(Human)
Centro De Investigaci£N Lilly

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)
Affinity DataKd:  1.81nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells measured over 90 secs by surface plasmon ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM784736(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Yme-Nal-Aib-Glu(...)
Affinity DataIC50: 1.95nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784737(Asp(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Yme-Nal-Aib-Orn(@1...)
Affinity DataIC50: 1.96nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784781(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Ala-Yme-Nal-Aib-Asp(...)
Affinity DataIC50: 2.06nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784766(Asp(Ac)(@1)-Asn-Thr-Wme-Gln-Arg-Yme-Nal-Aib-Orn(@1...)
Affinity DataIC50: 2.16nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784738(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Leu-Yme-Nak-Aib-Asp(...)
Affinity DataIC50: 2.47nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM50021396(CHEMBL3289607)
Affinity DataKd:  2.59nMAssay Description:Binding affinity to IL-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
LigandPNGBDBM784764(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Aib-Yme-Nal-Aib-Asp(...)
Affinity DataIC50: 2.68nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
TargetInterleukin-23 receptor(Human)
Centro De Investigaci£N Lilly

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)
Affinity DataIC50: 2.70nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as disruption of biotinylated IL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM784739(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Ala-Yme-Nak-Aib-Asp(...)
Affinity DataIC50: 2.74nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM128384(US8802721, 1)
Affinity DataIC50: 3nMAssay Description:Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50229786(5-[2,3-Dichloro-4-(5-{1-[2-((R)-2-guanidino-4-meth...)
Affinity DataEC50:  3nMAssay Description:Effective concentration required against phosphorylation of Mammary gland factor/STAT5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
LigandPNGBDBM784773(Ahx(@1)-Asn-Thr-Trp-Gln-Agb-Yme-Nal-Aib-Glu(@1)-As...)
Affinity DataIC50: 3.11nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784782(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Ala-Yme-Nal-Aib-Asp(...)
Affinity DataIC50: 3.13nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784765(Asp(Ac)(@1)-Asn-Thr-Wme-Gln-Arg-Tyr-Nal-Aib-Orn(@1...)
Affinity DataIC50: 3.36nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784740(Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Yme-Nak-Aib-Asp(@1...)
Affinity DataIC50: 3.55nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784769(Asp(Ac)(@1)-Asn-Thr-Wme-Gln-Arg-Yme-Nal-Leu-Orn(@1...)
Affinity DataIC50: 3.57nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784741(D-Lys(Ac)(@1)-Asn-Thr-Wme-Gln-Arg-Yme-Nal-Lys(Ac)-...)
Affinity DataIC50: 3.60nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784767(Glu(Ac)(@1)-Asn-Thr-Wme-Gln-Arg-Yme-Nal-Aib-Orn(@1...)
Affinity DataIC50: 4.55nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784777(Apt(@1)-Asn-Thr-Trp-Gln-Ala-Yme-Nal-Aib-Asp(@1)-As...)
Affinity DataIC50: 4.66nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649495(US11891386, Compound ARI-056)
Affinity DataIC50: 4.90nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

TargetInterleukin-2(Mouse)
Sandoz Pharma

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 5nMAssay Description:The compound was evaluated in vitro for the immunosuppressive activity in interleukin-2 by interleukin-2 reporter gene assay (IL2-RGA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterleukin-23 receptor(Human)
Centro De Investigaci£N Lilly

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)
Affinity DataIC50: 5.10nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as disruption of biotinylated IL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM784745(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Tyr-Nak-Aib-Asp(...)
Affinity DataIC50: 5.42nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784761(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Yme-Nal-Cit-Asp(...)
Affinity DataIC50: 5.63nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM784747(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Yme-Nak-Aib-Glu(...)
Affinity DataIC50: 5.74nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649503(US11891386, Compound ARI-148)
Affinity DataIC50: 5.90nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

LigandPNGBDBM784744(D-Asp(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Yme-Nal-Aib-Orn(...)
Affinity DataIC50: 6.24nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
TargetInterleukin-21(Human)
Ariagen

US Patent
LigandPNGBDBM649487(US11891386, Compound ARI-067)
Affinity DataIC50: 6.30nMAssay Description:IL-21 levels in cell supernatants and cell-free control samples were measured using the ALPHALISA assay kit from Perkin Elmer, following the manufact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent

TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM128386(US8802721, 3)
Affinity DataIC50: 6.40nMAssay Description:Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

LigandPNGBDBM784748(D-Lys(Ac)(@1)-Asn-Thr-Trp-Gln-Arg-Yme-Nak-Lys(Ac)-...)
Affinity DataIC50: 7.87nMMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
TargetInterleukin-2(Human)
The Second People'S Hospital of Fujian Provinc

Curated by ChEMBL
LigandPNGBDBM412467(US10399967, Compound 98 | N-(5-(5-ethyl-2-(5-methy...)
Affinity DataIC50: 8nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent

Displayed 1 to 50 (of 791 total ) | Next | Last >>
Jump to: