Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 6987
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163679(3,4‐Dichloro‐1‐benzothiophene...)
Affinity DataIC50: 220nMAssay Description:Gel-based assays were performed by combining 4 µL of OGG1 (62.5 nM) with 1 µL of inhibitor or buffer. Substrate (5 µL, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163680(3‐Chloro‐N'‐[(1Z)‐2...)
Affinity DataIC50: 270nMAssay Description:Gel-based assays were performed by combining 4 µL of OGG1 (62.5 nM) with 1 µL of inhibitor or buffer. Substrate (5 µL, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163683(N'‐Cyclohexylidene‐3‐hydroxy...)
Affinity DataIC50: 290nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163694(3‐Chloro‐1‐benzothiophene‐...)
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163681(3-Chloro‐N'‐[(1E)‐(4‐f...)
Affinity DataIC50: 330nMAssay Description:Gel-based assays were performed by combining 4 µL of OGG1 (62.5 nM) with 1 µL of inhibitor or buffer. Substrate (5 µL, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163683(N'‐Cyclohexylidene‐3‐hydroxy...)
Affinity DataIC50: 340nMAssay Description:Gel-based assays were performed by combining 4 µL of OGG1 (62.5 nM) with 1 µL of inhibitor or buffer. Substrate (5 µL, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163679(3,4‐Dichloro‐1‐benzothiophene...)
Affinity DataIC50: 350nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163680(3‐Chloro‐N'‐[(1Z)‐2...)
Affinity DataIC50: 370nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163695(Benzoylhydrazine, P‐bromo (0151-Hy))
Affinity DataIC50: 390nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163681(3-Chloro‐N'‐[(1E)‐(4‐f...)
Affinity DataIC50: 420nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163682(4‐Bromo‐N'‐cyclohexylidenebe...)
Affinity DataIC50: 610nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163682(4‐Bromo‐N'‐cyclohexylidenebe...)
Affinity DataIC50: 630nMAssay Description:Gel-based assays were performed by combining 4 µL of OGG1 (62.5 nM) with 1 µL of inhibitor or buffer. Substrate (5 µL, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163685(2‐(4‐Chloro‐3,5‐dimethylph...)
Affinity DataIC50: 1.53E+3nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163686(2‐(Naphthalen‐1‐yloxy)acetohydra...)
Affinity DataIC50: 1.56E+3nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163690(3‐Bromo‐N'‐[(2Z)‐hexan...)
Affinity DataIC50: 2.13E+3nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163684(2‐(3‐Chlorophenoxy)propanehydrazide (0...)
Affinity DataIC50: 3.38E+3nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163689(3‐Bromo‐N'‐[(2Z)‐hex&#...)
Affinity DataIC50: 3.78E+3nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163691(1‐(4‐Methoxy‐2,5‐dimethylb...)
Affinity DataIC50: 4.15E+3nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163688(2,4‐Dichloro‐N'‐(1‐pro...)
Affinity DataIC50: 4.56E+3nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163687(N'‐[(1E)‐1‐(2H‐1,3R...)
Affinity DataIC50: 7.17E+3nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163692(ISOCARBOXAZID | Marplan | Isocarboxazide | Isocarb...)
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM163693(Nialamide)
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM50336507(4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...)
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM50336507(4-pyridinecarbohydrazide(Isoniazid) | Dow-isoniazi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Gel-based assays were performed by combining 4 µL of OGG1 (62.5 nM) with 1 µL of inhibitor or buffer. Substrate (5 µL, 50 nM) was added to bring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM50106186(4-Bromo-benzamide | CHEMBL339059 | 4‐Bromobe...)
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetN-glycosylase/DNA lyase(Human)
Oregon Health & Science University

LigandPNGBDBM81461(NSC_3637 | CAS_86-54-4 | Hydralazine | Hydralazine...)
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:The fluorescence-based assay outlined in Figure 2 a was performed in black, low volume 384-well plates with a fi nal volume of 10 L per well. Nine uL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed