Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50010092
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535069(CHEMBL4448648)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase A128T mutant expressed in Escherichia coli BL21(DE3) cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50011132(CHEMBL3259891 | ALLINI-1)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535069(CHEMBL4448648)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as reduction in LED...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535069(CHEMBL4448648)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535069(CHEMBL4448648)
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of recombinant full length HIV1 C-terminal His-tagged integrase A128T mutant multimerization with N-terminal FLAG-tagged integrase A128T m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535069(CHEMBL4448648)
Affinity DataEC50:  1.61E+4nMAssay Description:Inhibition of recombinant full length HIV1 C-terminal His-tagged integrase multimerization with N-terminal FLAG-tagged integrase expressed in Escheri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535069(CHEMBL4448648)
Affinity DataIC50: 2.87E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged LEDGF/p75 binding to recombinant full length N-terminal His-tagged HIV1 integrase expressed in Escherichia coli ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535074(CHEMBL4460215)
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535073(CHEMBL4532605)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535072(CHEMBL4586384)
Affinity DataIC50: 4.41E+4nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535075(CHEMBL4573753)
Affinity DataIC50: 5.91E+4nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535071(CHEMBL4513790)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50535070(CHEMBL4462745)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged HIV1 integrase expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed