Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 600
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4227(benzyl N-[(1S)-1-{[(2S,3S)-4-[(2S)-2-(tert-butylca...)
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4216(Z.Asn-(2S,3S)-AHPBA-[4(S)-hydroxy]Pro tert-butylam...)
Affinity DataKi:  1nM ΔG°:  -53.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4224(benzyl N-[(1S)-1-{[(2S,3S)-4-[(2S)-2-(tert-butylca...)
Affinity DataKi:  1nM ΔG°:  -53.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4236((2S)-N-[(2S,3S)-4-[(2S,4S)-2-(tert-butylcarbamoyl)...)
Affinity DataKi:  4.5nM ΔG°:  -49.6kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4230((Quinoxaline-2-carbonyl)-Asn-(2S,3S)-AHPBA- [4(S)-...)
Affinity DataKi:  4.70nM ΔG°:  -49.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4218(benzyl N-[(1S)-1-{[(2S,3S)-4-[(2S)-2-(tert-butylca...)
Affinity DataKi:  8nM ΔG°:  -48.1kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4231((2S)-N-[(2S,3S)-4-[(2S,4S)-2-(tert-butylcarbamoyl)...)
Affinity DataKi:  12.5nM ΔG°:  -46.9kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4225(Z-Asn.(2S,3S)-AHPBA.(4.oxo)Pro tert-butylamide | b...)
Affinity DataKi:  12.5nM ΔG°:  -46.9kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4229(Z-Asn.(2S,3S)-AHPBA.[3(S)-chloro]Pro tert-butylami...)
Affinity DataKi:  14.5nM ΔG°:  -46.5kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4234((2S)-N-[(2S,3S)-4-[(2S,4S)-2-(tert-butylcarbamoyl)...)
Affinity DataKi:  16nM ΔG°:  -46.3kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4221(Z-Asn-(2S,3S)-AHPBA- [4(S)-fluoro] Pro tert-butyla...)
Affinity DataKi:  18nM ΔG°:  -46.0kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4233((1-Methylindole- 3 -carbonyl)- Asn - (2S,3S)-AHPBA...)
Affinity DataKi:  20nM ΔG°:  -45.7kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4232((2S)-N-[(2S,3S)-4-[(2S,4S)-2-(tert-butylcarbamoyl)...)
Affinity DataKi:  21.5nM ΔG°:  -45.5kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4220(Z-Asn-(2S,3S)-AHPBA.[4(S)-bromo]Pro tert-butylamid...)
Affinity DataKi:  22.5nM ΔG°:  -45.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4235((2S)-2-(1,2-benzoxazol-3-ylformamido)-N-[(2S,3S)-4...)
Affinity DataKi:  28nM ΔG°:  -44.8kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4228(Z.Asn-(2S,3S).AHPBA.[3(S)-hydroxy]Pro tert-butyl-a...)
Affinity DataKi:  32nM ΔG°:  -44.5kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4222(benzyl N-[(1S)-1-{[(2S,3S)-4-[(2S)-2-(tert-butylca...)
Affinity DataKi:  35nM ΔG°:  -44.3kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4217(benzyl N-[(1S)-1-{[(2S,3S)-4-[(2S,4R)-2-(tert-buty...)
Affinity DataKi:  56nM ΔG°:  -43.1kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4215(benzyl N-[(1S)-1-{[(2S,3S)-4-[(2S)-2-(tert-butylca...)
Affinity DataKi:  57.5nM ΔG°:  -43.0kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4219(Z-Asn-( 2S,3S).AHPBA. [ 4(R ).chloro ] Pro tert-bu...)
Affinity DataKi:  90nM ΔG°:  -41.8kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4226(benzyl N-[(1S)-1-{[(2S,3S)-4-[(2S)-2-(tert-butylca...)
Affinity DataKi:  92nM ΔG°:  -41.8kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sankyo

LigandPNGBDBM4223(Z.Asn-(2S,3S)-AHPBA-[ 4(S)-phenylthio]Pro tert-but...)
Affinity DataKi:  125nM ΔG°:  -41.0kJ/molepH: 4.7 T: 2°CAssay Description:The inhibitory activities of the compounds toward HIV-1 PR were determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2005
Entry Details Article
PubMed