BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 728K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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15 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Rational design of small-sized peptidomimetic inhibitors disrupting protein-protein interaction.EBI
Ningxia Medical University
Design, synthesis and anti-necroptosis activity of fused heterocyclic MLKL inhibitors.EBI
Ningxia Medical University
Curcumin hybrid molecules for the treatment of Alzheimer's disease: Structure and pharmacological activities.EBI
Ningxia Medical University
Scaffold hopping derived novel benzoxazepinone receptor-interacting protein kinase 1 (RIP1) inhibitors as anti-necroptosis agents: Anti-inflammatory effect in systemic inflammatory response syndrome (SIRS) and epilepsy.EBI
Ningxia Medical University
Targeting Receptor-Interacting Protein Kinase 1 by Novel Benzothiazole Derivatives: Treatment of Acute Lung Injury through the Necroptosis Pathway.EBI
Ningxia Medical University
Scaffold hopping derived novel benzoxazepinone RIPK1 inhibitors as anti-necroptosis agents.EBI
Ningxia Medical University
Structure-Based Design of Novel Alkynyl Thio-Benzoxazepinone Receptor-Interacting Protein Kinase-1 Inhibitors: Extending the Chemical Space from the Allosteric to ATP Binding Pockets.EBI
Ningxia Medical University
Crystallography-Guided Optimizations of the Keap1-Nrf2 Inhibitors on the Solvent Exposed Region: From Symmetric to Asymmetric Naphthalenesulfonamides.EBI
Ningxia Medical University
Investigation on the chemical space of the substituted triazole thio-benzoxazepinone RIPK1 inhibitors.EBI
Ningxia Medical University
Structure-based molecular hybridization design of Keap1-Nrf2 inhibitors as novel protective agents of acute lung injury.EBI
Ningxia Medical University
Enantiomeric profiling of a chiral benzothiazole necroptosis inhibitor.EBI
Ningxia Medical University
Discovery of natural product ellagic acid as a potent CD73 and CD39 dual inhibitor.EBI
Ningxia Medical University
-(7-Cyano-6-(4-fluoro-3-(2-(3-(trifluoromethyl)phenyl)acetamido)phenoxy)benzo[EBI
Ningxia Medical University
Inhibitor of Apoptosis Protein (IAP) Antagonists in Anticancer Agent Discovery: Current Status and Perspectives.EBI
Ningxia Medical University
Design and synthesis of novel PRMT1 inhibitors and investigation of their binding preferences using molecular modelling.EBI
Ningxia Medical University