38 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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2-Amido-8-methoxytetralins: a series of nonindolic melatonin-like agents.
University of Groningen
Design of a novel thiophene inhibitor of 15-lipoxygenase-1 with both anti-inflammatory and neuroprotective properties.
University of Groningen
Rational Development of a Potent 15-Lipoxygenase-1 Inhibitor with in Vitro and ex Vivo Anti-inflammatory Properties.
University of Groningen
Development of inhibitors of the 2C-methyl-D-erythritol 4-phosphate (MEP) pathway enzymes as potential anti-infective agents.
University of Groningen
Discovery of a novel activator of 5-lipoxygenase from an anacardic acid derived compound collection.
University of Groningen
Catalytic asymmetric total synthesis of (S)-(-)-zearalenone, a novel lipoxygenase inhibitor.
University of Groningen
Further characterization of structural requirements for ligands at the dopamine D(2) and D(3) receptor: exploring the thiophene moiety.
University of Groningen
Affinity for dopamine D2, D3, and D4 receptors of 2-aminotetralins. Relevance of D2 agonist binding for determination of receptor subtype selectivity.
University of Groningen
6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site.
University of Groningen
Reactivity of isothiazolones and isothiazolone-1-oxides in the inhibition of the PCAF histone acetyltransferase.
University of Groningen
Inhibition of the PCAF histone acetyl transferase and cell proliferation by isothiazolones.
University of Groningen
Allosteric Inhibitors of Macrophage Migration Inhibitory Factor (MIF) Interfere with Apoptosis-Inducing Factor (AIF) Co-Localization to Prevent Parthanatos.
University of Groningen
Synthetic Peptides That Antagonize the Angiotensin-Converting Enzyme-2 (ACE-2) Interaction with SARS-CoV-2 Receptor Binding Spike Protein.
University of Groningen
Design, Synthesis, and Biological Evaluation of Imidazopyridines as PD-1/PD-L1 Antagonists.
University of Groningen
Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF).
University of Groningen
Induced protein degradation of histone deacetylases 3 (HDAC3) by proteolysis targeting chimera (PROTAC).
University of Groningen
7-Hydroxycoumarins Are Affinity-Based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor.
University of Groningen
Discovery of Small-Molecule Stabilizers of 14-3-3 Protein-Protein Interactions via Dynamic Combinatorial Chemistry.
University of Groningen
New selective and potent 5-HT(1B/1D) antagonists: chemistry and pharmacological evaluation of N-piperazinylphenyl biphenylcarboxamides and biphenylsulfonamides.
University of Groningen
Synthesis and in vitro and in vivo functional studies of ortho-substituted phenylpiperazine and N-substituted 4-N-(o-methoxyphenyl)aminopiperidine analogues of WAY100635.
University of Groningen
A combinatorial approach for the discovery of drug-like inhibitors of 15-lipoxygenase-1.
University of Groningen
Novel 15-Lipoxygenase-1 Inhibitor Protects Macrophages from Lipopolysaccharide-Induced Cytotoxicity.
University of Groningen
Hitting on the move: Targeting intrinsically disordered protein states of the MDM2-p53 interaction.
University of Groningen
Inhibitory selectivity among class I HDACs has a major impact on inflammatory gene expression in macrophages.
University of Groningen
Synthesis and pharmacological evaluation of triflate-substituted analogues of clozapine: identification of a novel atypical neuroleptic.
University of Groningen
5-HT1D receptor agonist properties of novel 2-[5-[[(trifluoromethyl)sulfonyl]oxy]indolyl]ethylamines and their use as synthetic intermediates.
University of Groningen
2,30-Bis(10H-indole) heterocycles: New p53/MDM2/MDMX antagonists.
University of Groningen
Enzyme kinetics and inhibition of histone acetyltransferase KAT8.
University of Groningen
Druggability Assessment of Targets Used in Kinetic Target-Guided Synthesis.
University of Groningen
Discovery of chromenes as inhibitors of macrophage migration inhibitory factor.
University of Groningen
Chemoenzymatic Synthesis and Pharmacological Characterization of Functionalized Aspartate Analogues As Novel Excitatory Amino Acid Transporter Inhibitors.
University of Groningen
Photoactivation provides a mechanistic explanation for pan-assay interference behaviour of 2-aminopyrroles in lipoxygenase inhibition.
University of Groningen
Binding and functional characterization of alpha-2 adrenergic receptor subtypes on pig vascular endothelium.
Creighton University